SCHEMBL9993602

SCHEMBL9993602

CCCCCCOc1ncnc(-c2ccccc2)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 1/20 0.48
LTA4H P09960 1/20 0.41
MAPK8 P45983 1/20 0.41
PTPN1 P18031 1/20 0.40
GPR84 Q9NQS5 1/20 0.40
TLR8 Q9NR97 1/20 0.40
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
CDC7 O00311 1/20 0.39
PLK4 O00444 1/20 0.39
CHEK1 O14757 1/20 0.39
CHUK O15111 1/20 0.39
PDPK1 O15530 1/20 0.39
DYRK3 O43781 1/20 0.39
ROCK2 O75116 1/20 0.39
PRKD3 O94806 1/20 0.39
MAP4K4 O95819 1/20 0.39
PAK4 O96013 1/20 0.39
NTRK1 P04629 1/20 0.39
PRKCG P05129 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8520508 1.00 SOAT1 (0.48) SOAT1LTA4HMAPK8PTPN1GPR84
SCHEMBL27788939 0.94 CDC7 (0.44) SOAT1LTA4HMAPK8CDC7PLK4
SCHEMBL27615672 0.86 SOAT1 (0.55) SOAT1LTA4HPTPN1TLR8THRA
SCHEMBL15057526 0.82 ALDH1A1 (0.46) MAPK1TP53TSHR
SCHEMBL27875103 0.81 SOAT1 (0.50) SOAT1LTA4HPTPN1TLR8THRA
SCHEMBL28255891 0.80 GPR84 (0.51) GPR84RARBNR1H3TP53
SCHEMBL29051494 0.78 PTPN11 (0.51) SOAT1PTPN1RARBTP53TSHR
SCHEMBL29693771 0.78 PTPN11 (0.51) SOAT1PTPN1RARBTP53TSHR
SCHEMBL28598315 0.76 NR5A1 (0.48) LTA4HRARBTP53TSHR
SCHEMBL27536300 0.76 SOAT1 (0.51) SOAT1LTA4HPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8658285-B2 Optically clear UV and hydrolysis resistant polyester film TORAY PLASTICS (AMERICA), INC. (US) 2014-02-25 US disclosed
US-20110305913-A1 OPTICALLY CLEAR UV AND HYDROLYSIS RESISTANT POLYESTER FILM TORAY PLASTICS (AMERICA), INC. LUMIRROR DIVISION (US) 2011-12-15 US disclosed