Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.56 |
| ▸ | ADA | P00813 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561146 | 0.88 | DNMT3B (0.58) | DNMT3BADAKDM4EPKMP2RY1 | |
| SCHEMBL6709209 | 0.86 | DNMT3B (0.59) | DNMT3BADAKDM4EPKMADORA1 | |
| SCHEMBL3222906 | 0.85 | DNMT3B (0.56) | DNMT3BADAKDM4EPKMP2RY1 | |
| Nebularine SCHEMBL10666450 | 0.85 | ADA (0.65) | DNMT3BADAKDM4EPKMADORA1 | |
| Nebularine SCHEMBL745560 | 0.85 | ADA (0.65) | DNMT3BADAKDM4EPKMADORA1 | |
| Nebularine SCHEMBL29362246 | 0.85 | ADA (0.65) | DNMT3BADAKDM4EPKMADORA1 | |
| Nebularine SCHEMBL742475 | 0.85 | ADA (0.65) | DNMT3BADAKDM4EPKMADORA1 | |
| Nebularine SCHEMBL9644429 | 0.85 | ADA (0.65) | DNMT3BADAKDM4EPKMADORA1 | |
| Nebularine SCHEMBL29799158 | 0.85 | ADA (0.65) | DNMT3BADAKDM4EPKMADORA1 | |
| Nebularine SCHEMBL27552329 | 0.85 | ADA (0.65) | DNMT3BADAKDM4EPKMADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011500684-A | — | — | 2011-01-06 | — | — | JP | claimed |
| EP-2211854-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER USING BENZOPYRONE-TYPE PARP INHIBITORS | BiPar Sciences, Inc. (US) | 2010-08-04 | — | — | EP | claimed |
| WO-2009051815-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER USING BENZOPYRONE-TYPE PARP INHIBITORS | BIPAR SCIENCES, INC. (US) | 2009-04-23 | — | — | WO | claimed |
| EP-1909812-A2 | SMALL COMPOUNDS THAT CORRECT PROTEIN MISFOLDING AND USES THEREOF | University of Florida Research Foundation, Inc. (US) | 2008-04-16 | — | — | EP | claimed |
| EP-1856247-A2 | REGULATION OF AUTOPHAGY AND CELL SURVIVAL | The Trustees of The University of Pennsylvania (US) | 2007-11-21 | — | — | EP | claimed |
| WO-2007014327-A2 | SMALL COMPOUNDS THAT CORRECT PROTEIN MISFOLDING AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2007-02-01 | — | — | WO | claimed |
| WO-2006078774-A2 | REGULATION OF AUTOPHAGY AND CELL SURVIVAL | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-07-27 | — | — | WO | claimed |
| US-6841710-B2 | Instant degradation of plastics into soluble non-toxic products | ROSEN OREN (IL) | 2005-01-11 | — | — | US | claimed |
| US-20040064005-A1 | Instant degradation of plastics into soluble non-toxic products | ROSEN OREN (IL) | 2004-04-01 | — | — | US | claimed |
| US-20020156333-A1 | Instant degradation of plastics into soluble non-toxic products | ROSEN OREN (IL) | 2002-10-24 | — | — | US | claimed |
| WO-2002062924-A1 | INSTANT DEGRADATION OF PLASTICS TO SOLUBLE NON-TOXIC PRODUCTS | ROSEN OREN (IL) | 2002-08-15 | — | — | WO | claimed |
| EP-0674529-A1 | LIPID PRODRUGS FOR ORAL ADMINISTRATION | NeXstar Pharmaceuticals, Inc. (US) | 1995-10-04 | — | — | EP | claimed |
| WO-1994013324-A1 | LIPID PRODRUGS FOR ORAL ADMINISTRATION | VESTAR, INC. (US) | 1994-06-23 | — | — | WO | claimed |
| US-20240189230-A1 | PALM FOR THE TREATMENT OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY INCIDENTAL TO THE TREATMENT OF CANCER | PEPTINOVO BIOPHARMA INC. | 2024-06-13 | — | — | US | disclosed |
| WO-2024006994-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER BY TARGETING THE BRCA1 PSEUDOGENE 1 (BRCA1P1) | THE UNIVERSITY OF CHICAGO (US) | 2024-01-04 | — | — | WO | disclosed |
| EP-4241784-A2 | ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION | CureVac SE (DE) | 2023-09-13 | — | — | EP | disclosed |
| US-6258360-B1 | BENZOATE CONJUGATES; ANTITUMOR AGENTS | IGEN INTERNATIONAL, INC. | 2001-07-10 | — | — | US | disclosed |
| EP-0746336-A1 | PRODRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS | IGEN, INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| EP-0746336-A4 | PRODRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS | IGEN INC (US) | 1996-07-26 | — | — | EP | disclosed |
| WO-1993002703-A1 | PRODRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS | IGEN, INC. (US) | 1993-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240189230-A1 | PALM FOR THE TREATMENT OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY INCIDENTAL TO THE TREATMENT OF CANCER | SGMS1, PHOSPHO1, SGMS2 | DNMT3B 3213/4885ADA 2773/4885KDM4E 3744/4885 |
| US-20020156333-A1 | Instant degradation of plastics into soluble non-toxic products | REL, STRA6, RARA | DNMT3B 683/4885ADA 975/4885KDM4E 1774/4885 |
| US-20040064005-A1 | Instant degradation of plastics into soluble non-toxic products | RARA, REL, STRA6 | DNMT3B 676/4885ADA 1028/4885KDM4E 1846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.