Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 7/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656057 | 0.85 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR1BHTR6 | |
| SCHEMBL5502711 | 0.80 | HTR6 (0.43) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL4433033 | 0.78 | CYP1A2 (0.43) | SLC6A2SLC6A4SLC6A3HTR1BHTR6 | |
| SCHEMBL28031218 | 0.77 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3HTR1BKMT2A | |
| SCHEMBL9477676 | 0.77 | MCHR1 (0.51) | SLC6A2SLC6A4HTR1BHTR1DKMT2A | |
| SCHEMBL4982131 | 0.76 | CYP1A2 (0.56) | SLC6A2SLC6A4SLC6A3HTR1BHTR6 | |
| SCHEMBL6831487 | 0.76 | HTR1B (0.50) | SLC6A2SLC6A4HTR1BHTR6HTR1D | |
| SCHEMBL27614221 | 0.76 | SLC6A4 (0.58) | SLC6A2SLC6A4SLC6A3HTR1BHTR1D | |
| SCHEMBL5072033 | 0.75 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3HTR1BKMT2A | |
| SCHEMBL753956 | 0.75 | HPRT1 (0.41) | SLC6A2SLC6A4SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161690-A1 | PROCESSES FOR THE PREPARATION OF (+)-N,N-DIMETHYL-2-[1-(NAPHTHALENYLOXY) ETHYL] BENZENE METHANAMINE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |