Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 16/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 15/20 | 0.35 |
| ▸ | MCTS1 | Q9ULC4 | 9/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490874 | 0.91 | SLC16A3 (0.34) | TRPA1TRPV1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL2134837 | 0.86 | NPC1 (0.35) | TRPA1TRPV1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL45281 | 0.85 | TRPA1 (0.35) | TRPA1TRPV1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL45189 | 0.84 | TRPA1 (0.34) | TRPA1TRPV1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL2491219 | 0.84 | TRPA1 (0.33) | TRPA1TRPV1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL24287198 | 0.84 | TRPA1 (0.34) | TRPA1TRPV1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL30388183 | 0.83 | SCN9A (0.36) | TRPA1TRPV1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL2623668 | 0.83 | DHODH (0.36) | TRPA1TRPV1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL16530247 | 0.83 | TRPA1 (0.35) | TRPA1TRPV1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL16014772 | 0.82 | SLC16A3 (0.38) | TRPA1TRPV1SLC16A3SLC16A1MCTS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2955176-B1 | COMPOSITION COMPRISING CRYSTALLINE FORM B OF 1- (3-CHLOROPYRIDIN-2-YL)-N-[4-CYANO-2-METHYL-6-(METHYLCARBAMOYL)PHENYL]-3-([5-(TRIFLUOROMETHYL)-2H- TETRAZOL-2-YL]METHYL)-1H-PYRAZOL-5-CARBOXAMIDE AND ITS USE | BAYER IP GMBH (DE) | 2017-12-06 | — | — | EP | disclosed |
| EP-2955176-A1 | COMPOSITION COMPRISING CRYSTALLINE FORM B of 1- (3-CHLOROPYRIDIN-2-YL)-N-[4-CYANO-2-METHYL-6-(METHYLCARBAMOYL)PHENYL]-3-{[5-(TRIFLUOROMETHYL)-2H- TETRAZOL-2-YL]METHYL}-1H-PYRAZOL-5-CARBOXAMIDE AND ITS USE | Bayer Intellectual Property GmbH (DE) | 2015-12-16 | — | — | EP | disclosed |
| EP-2582694-B1 | PROCESS FOR MANUFACTURING TETRAZOLE- SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES AND NOVEL CRYSTALLINE MODIFICATION OF THESE DERIVATIVES | BAYER IP GMBH (DE) | 2015-07-22 | — | — | EP | disclosed |
| EP-2582694-A1 | PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILAMIDE DERIVATIVES AND NOVEL CRYSTAL POLYMORPH OF THESE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011157664-A1 | PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILAMIDE DERIVATIVES AND NOVEL CRYSTAL POLYMORPH OF THESE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-12-22 | — | — | WO | disclosed |