SCHEMBL2491219

SCHEMBL2491219

O=C(Cl)Oc1cc(Cn2nnc(C(F)(F)C(F)(F)C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.33
TRPV1 Q8NER1 1/20 0.33
SLC16A3 O15427 5/20 0.32
SLC16A1 P53985 5/20 0.32
MCTS1 Q9ULC4 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2490874 0.93 SLC16A3 (0.34) TRPA1TRPV1SLC16A3SLC16A1MCTS1
SCHEMBL2785709 0.87 SLC16A3 (0.32) TRPA1TRPV1SLC16A3SLC16A1
SCHEMBL2490872 0.85 SLC16A3 (0.33) TRPA1TRPV1SLC16A3SLC16A1MCTS1
SCHEMBL9995992 0.84 TRPA1 (0.36) TRPA1TRPV1SLC16A3SLC16A1MCTS1
SCHEMBL2244764 0.80 DHODH (0.32)
SCHEMBL16530144 0.78 TRPA1 (0.35) TRPA1TRPV1SLC16A3SLC16A1MCTS1
SCHEMBL24287198 0.77 TRPA1 (0.34) TRPA1TRPV1SLC16A3SLC16A1MCTS1
SCHEMBL2134837 0.75 NPC1 (0.35) TRPA1TRPV1SLC16A3SLC16A1MCTS1
SCHEMBL4346448 0.75 KDM4E (0.40) TRPA1TRPV1SLC16A3SLC16A1MCTS1
SCHEMBL30388183 0.75 SCN9A (0.36) TRPA1TRPV1SLC16A3SLC16A1MCTS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2379526-B1 Tetrazol-substituted anthranilic acid amides as pesticides BAYER IP GMBH (DE) 2015-05-27 EP disclosed
EP-2484676-B1 Tetrazol-substituted anthranilic acid amides as pesticides BAYER CROPSCIENCE AG (DE) 2015-01-21 EP disclosed
EP-2484676-A2 Tetrazol-substituted anthranilic acid amides as pesticides Bayer CropScience AG (DE) 2012-08-08 EP disclosed
EP-2379526-A2 TETRAZOLE SUBSTITUTED ANTHRANILIC ACID AMIDES AS PESTICIDES Bayer CropScience AG (DE) 2011-10-26 EP disclosed
WO-2010069502-A2 TETRAZOLE SUBSTITUTED ANTHRANILIC ACID AMIDES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2010-06-24 WO disclosed