Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.48 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.45 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9996046 | 0.98 | CYP19A1 (0.49) | CYP19A1CYP17A1CYP24A1CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL9996088 | 0.82 | CYP19A1 (0.59) | CYP19A1CYP17A1CYP24A1CYP3A4MAPT | |
| SCHEMBL11768069 | 0.82 | CYP24A1 (0.46) | CYP19A1CYP17A1CYP24A1CYP3A4MAPT | |
| SCHEMBL5329705 | 0.81 | CYP24A1 (0.48) | CYP19A1CYP17A1CYP24A1CYP3A4MAPT | |
| SCHEMBL29283781 | 0.81 | CYP19A1 (0.50) | CYP19A1CYP17A1CYP24A1CYP3A4MAPT | |
| SCHEMBL5305103 | 0.81 | KDM4E (0.55) | CYP19A1CYP17A1CYP24A1POLB | |
| SCHEMBL5301494 | 0.78 | CYP19A1 (0.55) | CYP19A1CYP17A1CYP24A1CYP11B1CYP11B2 | |
| SCHEMBL19494230 | 0.78 | CYP19A1 (0.51) | CYP19A1CYP17A1CYP24A1CYP3A4MAPT | |
| SCHEMBL5295918 | 0.77 | CYP19A1 (0.54) | CYP19A1CYP17A1CYP24A1 | |
| Dimethylamine SCHEMBL10651852 | 0.77 | KDM4E (0.54) | CYP19A1CYP17A1CYP24A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155445-A1 | Compounds and Methods for Treating Cancer and Diseases of the Central Nervous System | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2014-06-05 | — | — | US | disclosed |
| US-20110319459-A1 | Compounds and Methods for Treating Cancer and Diseases of the Central Nervous System | OSTA BIOTECHNOLOGIES (CA) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319459-A1 | Compounds and Methods for Treating Cancer and Diseases of the Central Nervous System | TXNRD2, HMOX1, HMOX2 | CYP19A1 884/4885CYP17A1 488/4885CYP24A1 1080/4885 |
| US-20140155445-A1 | Compounds and Methods for Treating Cancer and Diseases of the Central Nervous System | HMOX1, HMOX2, CYC1 | CYP19A1 641/4885CYP17A1 556/4885CYP24A1 1700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.