Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 5/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528132 | 0.83 | KCNMA1 (0.53) | KCNMA1SMN1; SMN2TSHRPTPRCPTPN1 | |
| SCHEMBL812320 | 0.77 | SMN1; SMN2 (0.43) | KCNMA1SMN1; SMN2TSHRPTPRCPTPN1 | |
| SCHEMBL20483754 | 0.77 | SMN1; SMN2 (0.40) | KCNMA1SMN1; SMN2TSHRPTPRCPTPN1 | |
| SCHEMBL8680885 | 0.76 | KCNMA1 (0.48) | KCNMA1SMN1; SMN2TSHRPTPRCPTPN1 | |
| SCHEMBL9627040 | 0.74 | KCNMA1 (0.46) | KCNMA1SMN1; SMN2TSHRPTPRCPTPN1 | |
| SCHEMBL9437945 | 0.72 | KCNMA1 (0.57) | KCNMA1SMN1; SMN2TSHRPTPRCPTPN1 | |
| SCHEMBL812171 | 0.71 | KCNMA1 (0.46) | KCNMA1SMN1; SMN2TSHRPTPRCPTPN1 | |
| SCHEMBL16713284 | 0.70 | SMN1; SMN2 (0.41) | KCNMA1SMN1; SMN2TSHRPTPRCPTPN1 | |
| SCHEMBL16314217 | 0.68 | SMN1; SMN2 (0.47) | KCNMA1SMN1; SMN2TSHRMAPTRAB9A | |
| SCHEMBL14871009 | 0.68 | KCNMA1 (0.50) | KCNMA1SMN1; SMN2TSHRMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110298143-A1 | COPOLYCARBONATE AND OPTICAL LENS | TEIJIN CHEMICALS LTD. (JP) | 2011-12-08 | — | — | US | disclosed |