Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.59 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.54 |
| ▸ | FEN1 | P39748 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 7/20 | 0.48 |
| ▸ | BCHE | P06276 | 4/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | KAT7 | O95251 | 1/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3326969 | 0.90 | ALOX5AP (0.57) | SCN9AALOX5APFEN1HTR6BCHE | |
| SCHEMBL3326965 | 0.90 | ALOX5AP (0.57) | SCN9AALOX5APFEN1HTR6BCHE | |
| SCHEMBL27157955 | 0.85 | SCN9A (0.55) | SCN9AALOX5APFEN1HTR6BCHE | |
| SCHEMBL3323433 | 0.84 | FEN1 (0.56) | SCN9AALOX5APFEN1HTR6BCHE | |
| SCHEMBL3323442 | 0.84 | FEN1 (0.56) | SCN9AALOX5APFEN1HTR6BCHE | |
| SCHEMBL27158910 | 0.84 | SCN9A (0.55) | SCN9AALOX5APFEN1HTR6BCHE | |
| SCHEMBL3323362 | 0.84 | SCN9A (0.55) | SCN9AALOX5APFEN1HTR6BCHE | |
| SCHEMBL3323355 | 0.84 | SCN9A (0.55) | SCN9AALOX5APFEN1HTR6BCHE | |
| SCHEMBL25200987 | 0.83 | RBP4 (0.54) | SCN9AALOX5APFEN1HTR6BCHE | |
| SCHEMBL29427741 | 0.83 | RBP4 (0.54) | SCN9AALOX5APFEN1HTR6BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-B1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS INC (US) | 2011-12-21 | — | — | EP | disclosed |