Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.57 |
| ▸ | FEN1 | P39748 | 4/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 7/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | KAT7 | O95251 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3326969 | 1.00 | ALOX5AP (0.57) | ALOX5APFEN1SCN9AHTR6BCHE | |
| SCHEMBL9996326 | 0.90 | SCN9A (0.59) | ALOX5APFEN1SCN9AHTR6BCHE | |
| SCHEMBL3323442 | 0.89 | FEN1 (0.56) | ALOX5APFEN1SCN9AHTR6BCHE | |
| SCHEMBL3323433 | 0.89 | FEN1 (0.56) | ALOX5APFEN1SCN9AHTR6BCHE | |
| SCHEMBL27157955 | 0.85 | SCN9A (0.55) | ALOX5APFEN1SCN9AHTR6BCHE | |
| SCHEMBL7946350 | 0.83 | FEN1 (0.55) | ALOX5APFEN1SCN9AHTR6BCHE | |
| SCHEMBL7946352 | 0.83 | FEN1 (0.55) | ALOX5APFEN1SCN9AHTR6BCHE | |
| SCHEMBL1866539 | 0.82 | ALOX5AP (0.57) | ALOX5APFEN1SCN9AACKR3KAT7 | |
| SCHEMBL1866537 | 0.82 | ALOX5AP (0.57) | ALOX5APFEN1SCN9AACKR3KAT7 | |
| SCHEMBL1769253 | 0.81 | CHEK2 (0.56) | ALOX5APFEN1SCN9AHTR6BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120858-A1 | Piperidine Derivatives | PFIZER INC. | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120858-A1 | Piperidine Derivatives | P2RX5, P2RX7, P2RX1 | ALOX5AP 2730/4885FEN1 4514/4885SCN9A 818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.