Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cyclohexanone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.73 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopentanone SCHEMBL8542126 | 0.97 | TRIM24 (0.71) | TRIM24TRIM33ALDH1A1CA1CA2 | |
| Cyclopentanone SCHEMBL28241904 | 0.93 | TRIM24 (0.67) | TRIM24TRIM33ALDH1A1CA1CA2 | |
| Cyclohexanone SCHEMBL375072 | 0.93 | — | — | |
| Cyclohexanone SCHEMBL999872 | 0.88 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1TSHRKDM4E | |
| Cyclohexanone SCHEMBL28536813 | 0.88 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1KMT2A | |
| Cyclohexanone SCHEMBL9421237 | 0.88 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1KMT2A | |
| Cyclohexanone SCHEMBL3600071 | 0.88 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1KMT2A | |
| Cycloheptanone SCHEMBL3602798 | 0.88 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1KMT2A | |
| SCHEMBL25380098 | 0.86 | TRIM24 (1.00) | TRIM24TRIM33ALDH1A1CA1CA2 | |
| SCHEMBL112034 | 0.86 | TRIM24 (1.00) | TRIM24TRIM33ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117753326-A | System and method for continuously producing poly (cyclohexylene carbonate) | 陕西煤业化工技术研究院有限责任公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117753063-A | Post-treatment and devolatilization system and method for producing polycyclohexanediate | 陕西煤业化工技术研究院有限责任公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117164840-A | Production process of carbon dioxide-based poly (cyclohexylene carbonate) | 陕西煤业化工技术研究院有限责任公司 | 2023-12-05 | — | — | CN | claimed |
| EP-3078374-B1 | INDOMETHACIN ANALOGS FOR THE TREATMENT OF CASTRATE-RESISTANT PROSTATE CANCER | UNIV VANDERBILT (US) | 2019-06-19 | — | — | EP | claimed |
| JP-2011500282-A | — | — | 2011-01-06 | — | — | JP | claimed |
| EP-2214598-A2 | RANDOM AMORPHOUS TERPOLYMER CONTAINING LACTIDE AND GLYCOLIDE | Abbott Cardiovascular Systems Inc. (US) | 2010-08-11 | — | — | EP | claimed |
| WO-2009055426-A2 | RANDOM AMORPHOUS TERPOLYMER CONTAINING LACTIDE AND GLYCOLIDE | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2009-04-30 | — | — | WO | claimed |
| EP-1589031-B1 | Production of polyketides and other natural products | BIOTICA TECH LTD (GB) | 2007-08-15 | — | — | EP | claimed |
| EP-1444206-B1 | SUBSTITUTED BENZO[B]AZEPIN-2-ONE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2006-03-15 | — | — | EP | claimed |
| JP-2005511570-A | — | — | 2005-04-28 | — | — | JP | claimed |
| WO-2003037870-A1 | SUBSTITUTED 1H-QUINOLIN-2-ONE COMPOUNDS | Grünenthal GmbH (DE) | 2003-05-08 | — | — | WO | claimed |
| WO-2003037863-A2 | SUBSTITUTED INDOLES, METHOD FOR PRODUCTION AND USE THEREOF FOR THE INHIBITION OF PAIN | Grünenthal GmbH (DE) | 2003-05-08 | — | — | WO | claimed |
| WO-2003037879-A1 | SUBSTITUTED (1H)-QUINOXALIN-2-ONE COMPOUNDS AND SUBSTITUTED 4-ARYL- AND 4-HETEROARYLCYCLOHEXANE COMPOUNDS | Grünenthal GmbH (DE) | 2003-05-08 | — | — | WO | claimed |
| WO-2003037873-A1 | SUBSTITUTED BENZO[B]AZEPIN-2-ONE COMPOUNDS | Grünenthal GmbH (DE) | 2003-05-08 | — | — | WO | claimed |
| EP-0287842-B1 | CURABLE COMPOSITIONS CONTAINING A MICHAEL-ADDITION PRODUCT, THEIR PREPARATION AND USE | BASF Lacke + Farben AG (DE) | 1991-06-12 | — | — | EP | claimed |
| WO-1991000922-A1 | PROCESS FOR PRODUCING LOWER ALKYL ESTERS OF R-(+)-3-OXOCYCLOALKANE CARBOXYLIC ACIDS | BOEHRINGER INGELHEIM KG (DE) | 1991-01-24 | — | — | WO | claimed |
| EP-0407909-A1 | Process for the preparation of R-(+)-3-oxo cycloalkane carboxylic lower alkyl esters | BOEHRINGER INGELHEIM KG (DE) | 1991-01-16 | — | — | EP | claimed |
| EP-0342205-A1 | HARDENABLE COMPOSITION ON THE BASIS OF A MICHAEL ADDITION PRODUCT, PROCESS FOR THE MANUFACTURE THEREOF AND USE THEREOF | BASF Lacke + Farben AG (DE) | 1989-11-23 | — | — | EP | claimed |
| EP-0287842-A1 | Curable compositions containing a Michael-addition product, their preparation and use | BASF Lacke + Farben AG (DE) | 1988-10-26 | — | — | EP | claimed |
| WO-1988007556-A1 | HARDENABLE COMPOSITION ON THE BASIS OF A MICHAEL ADDITION PRODUCT, PROCESS FOR THE MANUFACTURE THEREOF AND USE THEREOF | BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) | 1988-10-06 | — | — | WO | claimed |