Cyclohexanone

Cyclohexanone

SCHEMBL999872

O=C(O)S.O=C1CCCCC1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.65
TRIM33 Q9UPN9 2/20 0.65
ALDH1A1 P00352 1/20 0.65
TSHR P16473 1/20 0.30
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexanone SCHEMBL999716 0.88 TRIM24 (0.73) TRIM24TRIM33ALDH1A1TSHRKDM4E
Cyclohexanone SCHEMBL375072 0.87
Cyclopentanone SCHEMBL8542126 0.84 TRIM24 (0.71) TRIM24TRIM33ALDH1A1KDM4EPOLB
Cyclohexanone SCHEMBL9421237 0.82 TRIM24 (0.65) TRIM24TRIM33ALDH1A1
Cyclohexanone SCHEMBL28536813 0.82 TRIM24 (0.65) TRIM24TRIM33ALDH1A1
Cyclohexanone SCHEMBL3600071 0.82 TRIM24 (0.65) TRIM24TRIM33ALDH1A1
Cycloheptanone SCHEMBL3602798 0.82 TRIM24 (0.65) TRIM24TRIM33ALDH1A1
Cyclopentanone SCHEMBL28241904 0.81 TRIM24 (0.67) TRIM24TRIM33ALDH1A1KDM4EPOLB
SCHEMBL25380098 0.80 TRIM24 (1.00) TRIM24TRIM33ALDH1A1TSHR
Cyclohexanone SCHEMBL3299 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011500282-A 2011-01-06 JP claimed
EP-2214598-A2 RANDOM AMORPHOUS TERPOLYMER CONTAINING LACTIDE AND GLYCOLIDE Abbott Cardiovascular Systems Inc. (US) 2010-08-11 EP claimed
WO-2009055426-A2 RANDOM AMORPHOUS TERPOLYMER CONTAINING LACTIDE AND GLYCOLIDE ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2009-04-30 WO claimed
EP-2214598-A2 RANDOM AMORPHOUS TERPOLYMER CONTAINING LACTIDE AND GLYCOLIDE Abbott Cardiovascular Systems Inc. (US) 2010-08-11 EP disclosed
WO-2009055426-A2 RANDOM AMORPHOUS TERPOLYMER CONTAINING LACTIDE AND GLYCOLIDE ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2009-04-30 WO disclosed