Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 5/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9997474 | 0.79 | PFKFB3 (0.60) | PFKFB3ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL9997220 | 0.75 | PFKFB3 (0.80) | PFKFB3SIRT5ALDH1A1MEN1KMT2A | |
| SCHEMBL28657437 | 0.74 | PFKFB3 (0.59) | PFKFB3ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL28657585 | 0.73 | PFKFB3 (0.64) | PFKFB3SIRT5DCLRE1BALDH1A1MEN1 | |
| SCHEMBL9996898 | 0.73 | ACLY (0.63) | PFKFB3ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL9997006 | 0.73 | PFKFB3 (0.53) | PFKFB3ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL28637116 | 0.73 | ACLY (0.50) | PFKFB3ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL9997434 | 0.73 | PFKFB3 (0.69) | PFKFB3SIRT5ALDH1A1MEN1KMT2A | |
| SCHEMBL9997270 | 0.72 | ACLY (0.58) | PFKFB3ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL9997243 | 0.72 | ACLY (0.52) | PFKFB3ALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |