Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 4/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9997243 | 0.89 | ACLY (0.52) | ACLYMCL1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9996898 | 0.89 | ACLY (0.63) | ACLYMCL1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9997270 | 0.86 | ACLY (0.58) | ACLYMCL1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9996880 | 0.80 | HSD17B10 (0.58) | ACLYMCL1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9997350 | 0.80 | ALDH1A1 (0.52) | ACLYMCL1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9997207 | 0.80 | PFKFB3 (0.48) | ACLYMCL1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9997006 | 0.79 | PFKFB3 (0.53) | ACLYALDH1A1KMT2AHSD17B10MEN1 | |
| SCHEMBL9997474 | 0.79 | PFKFB3 (0.60) | ACLYMCL1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL15056109 | 0.78 | ACLY (0.52) | ACLYALDH1A1KMT2AHSD17B10MEN1 | |
| SCHEMBL15055055 | 0.77 | RORC (0.46) | ACLYALDH1A1KMT2AHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113396145-A | PFKFB3 inhibitors and uses thereof | 盖罗发现有限责任公司 | 2021-09-14 | — | — | CN | disclosed |