Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19281339 | 0.91 | LMNA (0.64) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL6673893 | 0.84 | TSHR (0.60) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL15055685 | 0.84 | LMNA (0.64) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL3500413 | 0.82 | ALDH1A1 (0.69) | LMNAALDH1A1MEN1KMT2APTPN5 | |
| SCHEMBL6674411 | 0.81 | LMNA (0.67) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9997084 | 0.80 | LMNA (0.68) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL1249879 | 0.79 | POLB (0.77) | LMNAALDH1A1MEN1KMT2APTPN5 | |
| SCHEMBL15055353 | 0.79 | TSHR (0.63) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9045755 | 0.79 | CA12 (0.76) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL6677289 | 0.78 | TSHR (0.59) | LMNAALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |