Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170372 | 0.90 | MAPK1 (0.40) | ADORA1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27212610 | 0.85 | MAPT (0.41) | ADORA1MAPTGAAL3MBTL1HTT | |
| SCHEMBL170677 | 0.84 | PDE2A (0.44) | ADORA1CYP1A2MAPTPDE2APDE10A | |
| SCHEMBL28165613 | 0.83 | MAPT (0.39) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL20698011 | 0.79 | CYP1A2 (0.43) | ADORA1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27212608 | 0.79 | RAB9A (0.45) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL20698000 | 0.79 | PDE2A (0.40) | ADORA1CYP1A2MAPTPDE2APDE10A | |
| SCHEMBL20697919 | 0.79 | PDE2A (0.36) | ADORA1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1726288 | 0.79 | PDE2A (0.39) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL23804413 | 0.79 | MAPT (0.39) | CYP1A2CYP3A4CYP2C19MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170223959-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2017-08-10 | — | — | US | claimed |
| EP-2403834-B1 | FUNGICIDAL PYRAZOLES | DU PONT (US) | 2015-12-02 | — | — | EP | claimed |
| US-20150230467-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2015-08-20 | — | — | US | claimed |
| US-9062005-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-06-23 | — | — | US | claimed |
| US-20110319430-A1 | FUNGICIDAL PYRAZOLES | E.I. DU PONT NEMOURS AND COMPANY (US) | 2011-12-29 | — | — | US | claimed |
| US-10448639-B2 | Fungicidal pyrazoles | FMC CORPORATION (US) | 2019-10-22 | — | — | US | disclosed |
| US-20170223959-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2017-08-10 | — | — | US | disclosed |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2017-06-01 | — | — | US | disclosed |
| US-9655361-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-05-23 | — | — | US | disclosed |
| US-9596853-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-03-21 | — | — | US | disclosed |
| EP-2403834-B1 | FUNGICIDAL PYRAZOLES | DU PONT (US) | 2015-12-02 | — | — | EP | disclosed |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2015-10-29 | — | — | US | disclosed |
| US-20150230467-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2015-08-20 | — | — | US | disclosed |
| US-9107412-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-08-18 | — | — | US | disclosed |
| US-9062005-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-06-23 | — | — | US | disclosed |
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-23 | — | — | US | disclosed |
| US-20110319430-A1 | FUNGICIDAL PYRAZOLES | E.I. DU PONT NEMOURS AND COMPANY (US) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319430-A1 | FUNGICIDAL PYRAZOLES | CBR3, CBR1, CYP2S1 | ADORA1 1061/4885CYP1A2 29/4885CYP3A4 6/4885 |
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | ADORA1 661/4885CYP1A2 27/4885CYP3A4 36/4885 |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | ADORA1 661/4885CYP1A2 27/4885CYP3A4 36/4885 |
| US-10448639-B2 | Fungicidal pyrazoles | CBR3, CBR1, CYP2S1 | ADORA1 1061/4885CYP1A2 29/4885CYP3A4 6/4885 |
| US-20150230467-A1 | FUNGICIDAL PYRAZOLES | CBR3, CBR1, CYP2S1 | ADORA1 1061/4885CYP1A2 29/4885CYP3A4 6/4885 |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | ADORA1 661/4885CYP1A2 27/4885CYP3A4 36/4885 |
| US-20170223959-A1 | FUNGICIDAL PYRAZOLES | CBR3, CBR1, CYP2S1 | ADORA1 1061/4885CYP1A2 29/4885CYP3A4 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.