Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543263 | 0.78 | — | — | |
| SCHEMBL30843554 | 0.73 | — | — | |
| SCHEMBL1189618 | 0.73 | JAK2 (0.33) | — | |
| SCHEMBL5796141 | 0.72 | NPC1 (0.37) | — | |
| SCHEMBL28325161 | 0.70 | JAK2 (0.32) | — | |
| SCHEMBL51476 | 0.69 | — | — | |
| SCHEMBL7639721 | 0.68 | TRIM24 (0.37) | ESR2 | |
| SCHEMBL2965185 | 0.68 | TRIM24 (0.37) | ESR2 | |
| SCHEMBL11227221 | 0.66 | — | — | |
| SCHEMBL1816717 | 0.66 | TRIM24 (0.35) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582692-A1 | CYCLOHEXYL-AZETIDINYL ANTAGONISTS OF CCR2 | Janssen Pharmaceutica, N.V. (BE) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159854-A1 | CYCLOHEXYL-AZETIDINYL ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2011-12-22 | — | — | WO | disclosed |