Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 4/20 | 0.43 |
| ▸ | NNMT | P40261 | 4/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18397623 | 0.82 | ALOX15 (0.39) | NNMTSIRT6MKNK1MKNK2F2 | |
| SCHEMBL18068142 | 0.75 | BCHE (0.36) | F2PLAUKLKB1ELANESIRT5 | |
| SCHEMBL30961137 | 0.74 | F2 (0.31) | F2PLAUKLKB1ELANESIRT5 | |
| SCHEMBL6685826 | 0.74 | — | — | |
| SCHEMBL28714120 | 0.72 | NNMT (0.44) | NNMTSIRT6MKNK1MKNK2KMT2A | |
| SCHEMBL28711105 | 0.71 | NNMT (0.43) | NNMTSIRT6MKNK1MKNK2POLB | |
| SCHEMBL164591 | 0.71 | — | — | |
| SCHEMBL6049125 | 0.71 | — | — | |
| SCHEMBL4106091 | 0.71 | — | — | |
| SCHEMBL23852412 | 0.70 | KMT2A (0.52) | F2POLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011160568-A1 | 3-METHOXY PYRAZOLE AMIDE COMPOUNDS AND USES THEREOF | 中国中化股份有限公司 (CN) | 2011-12-29 | — | — | WO | disclosed |