Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.63 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL9998666 | 0.97 | SLC22A1 (0.60) | SLC22A1SLC22A2TP53ALDH1A1CYP3A4 | |
| Tetrabuthylammonium SCHEMBL27990806 | 0.97 | SLC22A1 (0.67) | SLC22A1SLC22A2TP53ALDH1A1CYP3A4 | |
| Tetrabuthylammonium SCHEMBL243899 | 0.97 | SLC22A1 (0.67) | SLC22A1SLC22A2TP53ALDH1A1CYP3A4 | |
| Tetrabuthylammonium SCHEMBL1078546 | 0.95 | SLC22A1 (0.63) | SLC22A1SLC22A2TP53ALDH1A1CYP3A4 | |
| Tetrabuthylammonium SCHEMBL20550034 | 0.95 | SLC22A1 (0.63) | SLC22A1SLC22A2TP53ALDH1A1CYP3A4 | |
| Tetrabuthylammonium SCHEMBL28650063 | 0.95 | SLC22A1 (0.63) | SLC22A1SLC22A2TP53ALDH1A1CYP3A4 | |
| Tetrabuthylammonium SCHEMBL28652896 | 0.95 | SLC22A1 (0.63) | SLC22A1SLC22A2TP53ALDH1A1CYP3A4 | |
| Tetrabuthylammonium SCHEMBL28646345 | 0.95 | SLC22A1 (0.63) | SLC22A1SLC22A2TP53ALDH1A1CYP3A4 | |
| Tetrabuthylammonium SCHEMBL9795128 | 0.95 | SLC22A1 (0.63) | SLC22A1SLC22A2TP53ALDH1A1CYP3A4 | |
| Tetrabuthylammonium SCHEMBL27745678 | 0.95 | SLC22A1 (0.63) | SLC22A1SLC22A2TP53ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582655-B1 | METHOD FOR PRODUCING FILM-LIKE PRODUCT COMPRISING PI-ELECTRON CONJUGATED COMPOUND | RICOH CO LTD (JP) | 2022-03-30 | — | — | EP | disclosed |
| US-20160276110-A1 | ELECTROCHEMICAL DEVICE | PANASONIC CORPORATION (JP) | 2016-09-22 | — | — | US | disclosed |
| EP-3067906-A1 | ELECTROCHEMICAL DEVICE | Panasonic Corporation (JP) | 2016-09-14 | — | — | EP | disclosed |
| US-9356292-B2 | Radical composition and battery using same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2016-05-31 | — | — | US | disclosed |
| US-9013023-B2 | Photoelectric element having stacked charge-transport layers | PANASONIC CORPORATION (JP) | 2015-04-21 | — | — | US | disclosed |
| US-20140070202-A1 | PHOTOELECTRIC ELEMENT | PANASONIC CORPORATION (JP) | 2014-03-13 | — | — | US | disclosed |
| US-20140061532-A1 | RADICAL COMPOSITION AND BATTERY USING SAME | WASEDA UNIVERSITY (JP) | 2014-03-06 | — | — | US | disclosed |
| EP-2582655-A1 | LEAVING SUBSTITUENT-CONTAINING COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL FORMED THEREFROM, ORGANIC ELECTRONIC DEVICE, ORGANIC THIN-FILM TRANSISTOR AND DISPLAY DEVICE USING THE ORGANIC SEMICONDUCTOR MATERIAL, METHOD FOR PRODUCING FILM-LIKE PRODUCT, PI-ELECTRON CONJUGATED COMPOUND AND METHOD FOR PRODUCING THE PI-ELECTRON CONJUGATED COMPOUND | Ricoh Company, Ltd. (JP) | 2013-04-24 | — | — | EP | disclosed |
| US-20130095605-A1 | LEAVING SUBSTITUENT-CONTAINING COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL FORMED THEREFROM, ORGANIC ELECTRONIC DEVICE, ORGANIC THIN-FILM TRANSISTOR AND DISPLAY DEVICE USING THE ORGANIC SEMICONDUCTOR MATERIAL, METHOD FOR PRODUCING FILM-LIKE PRODUCT, PI-ELECTRON CONJUGATED COMPOUND AND METHOD FOR PRODUCING THE PI ELECTRON CONJUGATED COMPOUND | RICOH COMPANY, LTD. (JP) | 2013-04-18 | — | — | US | disclosed |
| WO-2011158953-A1 | LEAVING SUBSTITUENT-CONTAINING COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL FORMED THEREFROM, ORGANIC ELECTRONIC DEVICE, ORGANIC THIN-FILM TRANSISTOR AND DISPLAY DEVICE USING THE ORGANIC SEMICONDUCTOR MATERIAL, METHOD FOR PRODUCING FILM-LIKE PRODUCT, PI-ELECTRON CONJUGATED COMPOUND AND METHOD FOR PRODUCING THE PI-ELECTRON CONJUGATED COMPOUND | RICOH COMPANY, LTD. (JP) | 2011-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130095605-A1 | LEAVING SUBSTITUENT-CONTAINING COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL FORMED THEREFROM, ORGANIC ELECTRONIC DEVICE, ORGANIC THIN-FILM TRANSISTOR AND DISPLAY DEVICE USING THE ORGANIC SEMICONDUCTOR MATERIAL, METHOD FOR PRODUCING FILM-LIKE PRODUCT, PI-ELECTRON CONJUGATED COMPOUND AND METHOD FOR PRODUCING THE PI ELECTRON CONJUGATED COMPOUND | THEM6, ORMDL3, INTS6 | SLC22A1 931/4885SLC22A2 745/4885TP53 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.