Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794186 | 0.83 | L3MBTL1 (0.48) | L3MBTL1KDM4EFPR2LMNACACNA1H | |
| Ornithine SCHEMBL3801712 | 0.81 | GSR (0.36) | MEN1KMT2AGAAGSRTDP1 | |
| Ornithine SCHEMBL3801714 | 0.78 | GSR (0.39) | GSR | |
| Lysine SCHEMBL28681105 | 0.74 | GSR (0.54) | GSR | |
| Lysine SCHEMBL31606629 | 0.74 | GSR (0.54) | GSR | |
| SCHEMBL4734573 | 0.71 | STK17B (0.47) | MEN1KMT2AGAAL3MBTL1TDP1 | |
| SCHEMBL4713820 | 0.71 | NPSR1 (0.47) | L3MBTL1TDP1NPSR1 | |
| SCHEMBL3845409 | 0.70 | MEN1 (0.42) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL24872799 | 0.70 | MEN1 (0.45) | MEN1KMT2AGAAKDM4ETDP1 | |
| SCHEMBL12463276 | 0.70 | MEN1 (0.73) | MEN1KMT2AGAAGSRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110312877-A1 | ENGINEERED TUNABLE NANOPARTICLES FOR DELIVERY OF THERAPEUTICS, DIAGNOSTICS, AND EXPERIMENTAL COMPOUNDS AND RELATED COMPOSITIONS FOR THERAPEUTIC USE | APARNA BIOSCEIENCES (US) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312877-A1 | ENGINEERED TUNABLE NANOPARTICLES FOR DELIVERY OF THERAPEUTICS, DIAGNOSTICS, AND EXPERIMENTAL COMPOUNDS AND RELATED COMPOSITIONS FOR THERAPEUTIC USE | TLR3, CHIA, TSG101 | MEN1 2240/4885KMT2A 2770/4885GAA 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.