Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2341431 | 0.88 | IP6K1 (0.40) | MAPTALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL2343390 | 0.87 | MEN1 (0.43) | MAPTALDH1A1HPGDHSD17B10TARBP2 | |
| SCHEMBL1286656 | 0.86 | LPAR1 (0.48) | L3MBTL1MAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9998264 | 0.85 | LPAR1 (0.48) | L3MBTL1MAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2335059 | 0.85 | LPAR1 (0.41) | L3MBTL1MAPTALDH1A1HSD17B10PKM | |
| SCHEMBL2225515 | 0.85 | LPAR1 (0.41) | L3MBTL1MAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6694 | 0.83 | LPAR1 (0.50) | MAPTALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL7595 | 0.83 | OPRM1 (0.44) | CYP2C9LPAR1 | |
| SCHEMBL2635812 | 0.82 | OPRM1 (0.43) | ALDH1A1CYP1A2CYP2C9LPAR1TSHR | |
| SCHEMBL3714448 | 0.82 | LPAR1 (0.41) | MAPTTP53LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159550-A2 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONIST AND USES THEREOF | AMIDRA PHARMACEUTICALS, INC. (US) | 2011-12-22 | — | — | WO | disclosed |