Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9999214 | 0.81 | — | — | |
| SCHEMBL6688612 | 0.68 | DNM1 (0.34) | — | |
| SCHEMBL11051720 | 0.67 | DNM1 (0.33) | — | |
| SCHEMBL11051722 | 0.67 | DNM1 (0.33) | — | |
| SCHEMBL28170330 | 0.66 | ALDH1A1 (0.40) | — | |
| SCHEMBL9998558 | 0.65 | — | — | |
| SCHEMBL13130604 | 0.64 | SMN1; SMN2 (0.35) | GPR119 | |
| SCHEMBL1781072 | 0.63 | DNM1 (0.50) | — | |
| SCHEMBL11955251 | 0.62 | SMN1; SMN2 (0.46) | GPR119 | |
| SCHEMBL12276212 | 0.62 | DNM1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582692-A1 | CYCLOHEXYL-AZETIDINYL ANTAGONISTS OF CCR2 | Janssen Pharmaceutica, N.V. (BE) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159854-A1 | CYCLOHEXYL-AZETIDINYL ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2011-12-22 | — | — | WO | disclosed |