Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 3/20 | 0.63 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4140615 | 0.79 | ALOX5 (0.60) | MLYCDLTB4R2 | |
| SCHEMBL9998819 | 0.78 | POLQ (0.61) | MLYCDCNR2NR1H2NR1H3KCNH2 | |
| SCHEMBL9295793 | 0.77 | TP53 (0.62) | CNR2NPC1JAK2RAB9APAX8 | |
| SCHEMBL2942439 | 0.77 | MLYCD (1.00) | MLYCDNR1H2NR1H3 | |
| SCHEMBL5822143 | 0.77 | NPC1 (0.54) | MLYCDNR1H2NR1H3NPC1JAK2 | |
| SCHEMBL6543341 | 0.75 | NPC1 (0.59) | MLYCDCNR2NPC1JAK2RAB9A | |
| SCHEMBL3647497 | 0.74 | PTGDR2 (0.49) | LTB4R2 | |
| SCHEMBL9307974 | 0.73 | CNR2 (0.62) | CNR2LTB4R2 | |
| SCHEMBL19049114 | 0.73 | NPC1 (0.67) | MLYCDNPC1JAK2RAB9APAX8 | |
| SCHEMBL9483626 | 0.72 | MEN1 (0.53) | MLYCDCNR2NPC1RAB9AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822519-B2 | Compound with agitation effect on peroxisome proliferator-activated receptor process for its preparation and use thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2014-09-02 | — | — | US | disclosed |
| US-20110319458-A1 | COMPOUND WITH AGITATION EFFECT ON PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR. PROCESS FOR ITS PREPARATION AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319458-A1 | COMPOUND WITH AGITATION EFFECT ON PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR. PROCESS FOR ITS PREPARATION AND USE THEREOF | PPARG, PPARD, PPARA | MLYCD 427/4885CNR2 809/4885NR1H2 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.