Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9999825 | 0.87 | HDAC3 (0.58) | SMN1; SMN2HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL13328782 | 0.86 | SMN1; SMN2 (0.79) | SMN1; SMN2NAAALMNAGAAL3MBTL1 | |
| SCHEMBL5662781 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2LMNAHDAC1HDAC2GAA | |
| SCHEMBL13878432 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2HDAC1HDAC2GAAL3MBTL1 | |
| SCHEMBL15170741 | 0.84 | NPC1 (0.58) | NAAAHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL15237259 | 0.84 | NPC1 (0.58) | NAAAHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL15235389 | 0.84 | NPC1 (0.58) | NAAAHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL9925387 | 0.84 | NPC1 (0.58) | NAAAHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL15235382 | 0.84 | NPC1 (0.58) | NAAAHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL27563409 | 0.84 | LMNA (0.68) | SMN1; SMN2NAAALMNAHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053293-A1 | SALT RESISTANT SEMI-AROMATIC COPOLYAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (DE) | 2012-03-01 | — | — | US | disclosed |