Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 8/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9999796 | 0.87 | SMN1; SMN2 (0.62) | HDAC3HDAC1HDAC4HDAC2HDAC8 | |
| SCHEMBL15237259 | 0.86 | NPC1 (0.58) | HDAC3HDAC1HDAC4HDAC2HDAC8 | |
| SCHEMBL15170741 | 0.86 | NPC1 (0.58) | HDAC3HDAC1HDAC4HDAC2HDAC8 | |
| SCHEMBL15235389 | 0.86 | NPC1 (0.58) | HDAC3HDAC1HDAC4HDAC2HDAC8 | |
| SCHEMBL15235382 | 0.86 | NPC1 (0.58) | HDAC3HDAC1HDAC4HDAC2HDAC8 | |
| SCHEMBL9925387 | 0.86 | NPC1 (0.58) | HDAC3HDAC1HDAC4HDAC2HDAC8 | |
| SCHEMBL13165401 | 0.81 | ALDH1A1 (0.63) | HDAC3HDAC1HDAC4HDAC2HDAC8 | |
| SCHEMBL12422572 | 0.79 | HDAC1 (0.74) | HDAC3HDAC1HDAC4HDAC2HDAC8 | |
| SCHEMBL15985477 | 0.79 | XDH (0.51) | HDAC3HDAC1HDAC4HDAC2HDAC8 | |
| SCHEMBL8479142 | 0.78 | HDAC3 (0.64) | HDAC3HDAC1HDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053294-A1 | SEMI-AROMATIC COPOLYAMIDE COMPOSITIONS WITH IMPROVED SALT RESISTANCE AND HIGH TEMPERTURE PROPERTIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-01 | — | — | US | disclosed |