COPB2

Coatomer subunit beta' · P35606 · COPB2 on Sugi Atlas →

0 patent compounds predicted against COPB2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to COPB2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Phenotype/Genotype Correlations in Neuromuscular Disorders nanCOMPLETED
Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam nanUNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Implementation of Molecular Diagnostic Pathways nanUNKNOWN
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others nanRECRUITING
Study of Constitutional Platelet Disease nanUNKNOWN
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Presymptomatic Neuromuscular Junction Defects and Compensatory Mechanisms in ALS nanUNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS) nanRECRUITING
ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study nanACTIVE_NOT_RECRUITING
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease nanCOMPLETED
The Influence of Genetic Variations in ELAPOR1 or ELAPOR2 on Insulin Secretion and Glucose Regulation in Humans nanUNKNOWN
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Study of ALS Reversals 2: Genetic Analyses nanCOMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
A Multicentric European Study to Promote Clinical Trial Readiness for STXBP1-related Disorders nanRECRUITING
Gene Analysis of Parkinson's Disease nanCOMPLETED
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a COPB2 binder may also engage these)

ProteinNameSimilarity
Q4R4I8 1.000 Q4R4I8 →
O55029 1.000 O55029 →
P35605 1.000 P35605 →
Q5R664 1.000 Q5R664 →
O35142 1.000 O35142 →
Q9CAA0 0.986 Q9CAA0 →
Q9C827 0.984 Q9C827 →
Q6H8D6 0.984 Q6H8D6 →
Q6NWV3 0.982 Q6NWV3 →
Q8L828 0.982 Q8L828 →
Q6H8D5 0.982 Q6H8D5 →
A8WGF4 0.981 A8WGF4 →
Q5VQ78 0.980 Q5VQ78 →
Q9HBG6 0.978 Q9HBG6 →
AP2A1 AP-2 complex subunit alpha-1 0.971 landscape →
Q94899 0.970 Q94899 →
Q3UGF1 0.969 Q3UGF1 →
Q8K2G4 0.968 Q8K2G4 →
Q68FS2 0.968 Q68FS2 →
Q5R922 0.967 Q5R922 →
D2SW95 0.967 D2SW95 →
Q6P0H6 0.967 Q6P0H6 →
O88544 0.966 O88544 →
Q3SZA0 0.966 Q3SZA0 →
Q9JIF7 0.965 Q9JIF7 →
P17426 0.965 P17426 →
Q8IWZ6 0.964 Q8IWZ6 →
A7Y521 0.962 A7Y521 →
COPS4 COP9 signalosome complex subunit 4 0.962 landscape →
Q4R5E6 0.962 Q4R5E6 →