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BMPR1A

Bone morphogenetic protein receptor type-1A · P36894 · BMPR1A on Sugi Atlas →

19,262 patent compounds predicted against BMPR1A, 11,240 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL751228 SCHEMBL751228 0.67 18/20
SCHEMBL746558 SCHEMBL746558 0.61 18/20
SCHEMBL746559 SCHEMBL746559 0.61 18/20
SCHEMBL768827 SCHEMBL768827 0.59 18/20
SCHEMBL745958 SCHEMBL745958 0.67 17/20
SCHEMBL768977 SCHEMBL768977 0.67 17/20
SCHEMBL769523 SCHEMBL769523 0.65 17/20
SCHEMBL769524 SCHEMBL769524 0.65 17/20
SCHEMBL745462 SCHEMBL745462 0.62 17/20
SCHEMBL756281 SCHEMBL756281 0.62 17/20
SCHEMBL768914 SCHEMBL768914 0.61 17/20
SCHEMBL768999 SCHEMBL768999 0.58 17/20
SCHEMBL769000 SCHEMBL769000 0.58 17/20
SCHEMBL768711 SCHEMBL768711 0.56 17/20
SCHEMBL754134 SCHEMBL754134 0.54 17/20
SCHEMBL769221 SCHEMBL769221 0.73 16/20
SCHEMBL769234 SCHEMBL769234 0.71 16/20
SCHEMBL744757 SCHEMBL744757 0.69 16/20
SCHEMBL753680 SCHEMBL753680 0.68 16/20
SCHEMBL750197 SCHEMBL750197 0.67 16/20

Clinical trials — most relevant to BMPR1A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Vitamin D and Carboxy PTH Fragments in Coronary Calcification PHASE4WITHDRAWN
Socket Augmentation Using Atorvastatin With Or Without PRGF (Clinical and Histomorphometric Study) PHASE4COMPLETED
The Use of Adhesion Molecule Loaded Hydrogel With Minimally Invasive Surgical Technique in Treatment of Periodontal Intrabony Defect PHASE1/PHASE2COMPLETED
A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor PHASE1/PHASE2COMPLETED
Pharmacokinetics, Safety and Efficacy of BIA 5-1058 in PAH (Zamicastat) PHASE2COMPLETED
ALlogeneic Cardiosphere-derived Stem Cells (CDCs) for Pulmonary Hypertension therApy PHASE1COMPLETED
Short-term Impact of Cyplexinol® on Self-reported Joint Pain nanCOMPLETED
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies nanUNKNOWN
Effect of BMPR-2 Gene Mutations on Hemodynamic Response by Iloprost Inhalation in Pulmonary Arterial Hypertension nanCOMPLETED
Genetic and Environmental Characteristics of Primary Pulmonary Hypertension nanCOMPLETED
StratosPHere (Non-interventional Study) nanCOMPLETED
Genes-in-Action - Hepcidin Regulation of Iron Supplementation nanCOMPLETED
Screening of Pulmonary Arterial Hypertension in BMPR2 Mutation Carriers nanCOMPLETED
Role of Novel Biomarkers Associated With In-stent Restenosis After Percutaneous Coronary Intervention nanUNKNOWN
TranspulmonarY Estrogen Gradient and Estrogen Receptors (TYEGER) in PAH nanWITHDRAWN
Assessment of the TGF-beta Pathway and Micro-RNA in Pediatric Pulmonary Arterial Hypertension nanUNKNOWN
Immediate Implants in Maxillary Premolar Region Using Xenograft vs Allograft nanUNKNOWN
BMPR2 Mutations and Iron Metabolism in Pulmonary Arterial Hypertension nanCOMPLETED
Genetics of Pulmonary Hypertension nanUNKNOWN
National Cohort Study of Idiopathic and Heritable Pulmonary Arterial Hypertension nanUNKNOWN
Induce XT™ Bone Graft in Foot and Ankle Fusion nanENROLLING_BY_INVITATION
Osteoprosis in Type 2 Diabetic Patients- a Cohort Study nanUNKNOWN
The PAH Platform for Deep Phenotyping in Korean Subjects nanUNKNOWN
Roles of microRNAs in the Development of Osteoporosis in Men - Preliminary Study nanUNKNOWN
Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals nanRECRUITING
Target of Suv420h1/2 in Hepatocytes nanRECRUITING
Exhaled Breath Olfactory Signature of Pulmonary Arterial Hypertension nanCOMPLETED
AO CSH Mainstream Study on Cervical Spine Degeneration nanNOT_YET_RECRUITING
Autogenous Demineralized Dentin Block Graft Versus Particulate Deproteinized Bovine Bone Graft for Alveolar Ridge Preservation nanUNKNOWN
Therapeutic Irrigation Procedures to Treat Apical Periodontitis nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a BMPR1A binder may also engage these)

ProteinNameSimilarity
Q78EA7 — 1.000 Q78EA7 →
BMPR1B Bone morphogenetic protein receptor type-1B 1.000 landscape →
P37172 — 1.000 P37172 →
P36895 — 1.000 P36895 →
P80201 — 1.000 P80201 →
Q05438 — 0.998 Q05438 →
TGFBR1 TGF-beta receptor type-1 0.997 landscape →
P80202 — 0.997 P80202 →
Q61271 — 0.996 Q61271 →
P80204 — 0.996 P80204 →
Q64729 — 0.996 Q64729 →
P36898 — 0.995 P36898 →
A1Z7L8 — 0.993 A1Z7L8 →
ACVR1 Activin receptor type-1 0.992 landscape →
Q28041 — 0.992 Q28041 →
Q5CD18 — 0.992 Q5CD18 →
Q90ZK6 — 0.992 Q90ZK6 →
O46680 — 0.992 O46680 →
P70539 — 0.990 P70539 →
Q09488 — 0.990 Q09488 →
ACVR1B Activin receptor type-1B 0.990 landscape →
Q24468 — 0.989 Q24468 →
Q9GYQ4 — 0.987 Q9GYQ4 →
Q90344 — 0.987 Q90344 →
Q8NER5 — 0.986 Q8NER5 →
Q60629 — 0.986 Q60629 →
O42422 — 0.986 O42422 →
Q8AXC7 — 0.985 Q8AXC7 →
P20792 — 0.985 P20792 →
Q9QVP9 — 0.985 Q9QVP9 →