SCHEMBL276090

SCHEMBL276090

O=c1c2ccccc2[nH]c2c(=O)c3ccc(Cl)cc3[nH]c12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 3/20 0.66
CCND1 P24385 3/20 0.66
CAMK2B Q13554 3/20 0.66
CAMK2G Q13555 3/20 0.66
CAMK2D Q13557 3/20 0.66
CAMK2A Q9UQM7 3/20 0.66
CCNE2 O96020 2/20 0.66
CCNE1 P24864 2/20 0.66
CDK2 P24941 2/20 0.66
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
GABRP O00591 1/20 0.54
GABRD O14764 1/20 0.54
GABRA1 P14867 1/20 0.54
GABRB1 P18505 1/20 0.54
GABRG2 P18507 1/20 0.54
GABRB3 P28472 1/20 0.54
GABRA5 P31644 1/20 0.54
GABRA3 P34903 1/20 0.54
GABRA2 P47869 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4231006 0.89 GAA (0.67) CDK4CCND1CAMK2BCAMK2GCAMK2D
SCHEMBL5621445 0.83 ALDH1A1 (0.73) CDK4CCND1CAMK2BCAMK2GCAMK2D
SCHEMBL4670015 0.81 AHR (0.64) CDK4CCND1CAMK2BCAMK2GCAMK2D
SCHEMBL30659227 0.81 AHR (0.64) CDK4CCND1CAMK2BCAMK2GCAMK2D
SCHEMBL8127691 0.80 CDK4 (1.00) CDK4CCND1CAMK2BCAMK2GCAMK2D
SCHEMBL276017 0.79 ALDH1A1 (0.65) CDK4CCND1CAMK2BCAMK2GCAMK2D
SCHEMBL14598929 0.79 KDM4E (0.62) CDK4CCND1CAMK2BCAMK2GCAMK2D
SCHEMBL7846565 0.79 ALDH1A1 (0.67) CDK4CCND1CAMK2BCAMK2GCAMK2D
SCHEMBL30704463 0.79 ALDH1A1 (0.67) CDK4CCND1CAMK2BCAMK2GCAMK2D
SCHEMBL14543827 0.79 PARP1 (0.62) CDK4CCND1CAMK2BCAMK2GCAMK2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133311-B2 Liquid vehicle, pigment, and non-polymeric dispersant containing diphosphate groups; ink jet inks CABOT CORPORATION (US) 2012-03-13 US disclosed
US-8133311-B2 Liquid vehicle, pigment, and non-polymeric dispersant containing diphosphate groups; ink jet inks CABOT CORPORATION (US) 2012-03-13 US disclosed
US-20110207860-A1 Inkjet Ink Compositions Comprising Polymeric Dispersants Having Attached Chromophore Groups CABOT CORPORATION (US) 2011-08-25 US disclosed
US-7947761-B2 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION (US) 2011-05-24 US disclosed
US-20080264298-A1 Pigment dipsersions comprising functionalized non-polymeric dispersants CABOT CORPORATION 2008-10-30 US disclosed
US-20080264298-A1 Pigment dipsersions comprising functionalized non-polymeric dispersants CABOT CORPORATION 2008-10-30 US disclosed
WO-2007089859-A1 INKJET INK COMPOSITIONS COMPRISING POLYMERIC DISPERSANTS HAVING ATTACHED CHROMOPHORE GROUPS CABOT CORPORATION (US) 2007-08-09 WO disclosed
US-20070179214-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179213-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179215-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179215-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179213-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179214-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed