CCT8

T-complex protein 1 subunit theta · P50990 · CCT8 on Sugi Atlas →

0 patent compounds predicted against CCT8, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to CCT8 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers PHASE1/PHASE2COMPLETED
I/II Phase Study Evaluating M1774 in Combination With Fulvestrant in HR+ and HER2- Advanced Breast Cancers PHASE1/PHASE2NOT_YET_RECRUITING
Danazol for Genetic Bone Marrow and Lung Disorders PHASE1/PHASE2COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors PHASE1COMPLETED
5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors PHASE1RECRUITING
Single-Dose AAV-MECP2 Safety/Tolerability and Efficacy in Rett Syndrome EARLY_PHASE1ACTIVE_NOT_RECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility nanRECRUITING
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Pathogenetic Basis of Aortopathy and Aortic Valve Disease nanACTIVE_NOT_RECRUITING
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) nanRECRUITING
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm nanCOMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Genetic Diagnosis in Congenital Cataracts nanCOMPLETED
Genetics and Psychopathology in the 22q11 Deletion Syndrome nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Correlation Between Myocardial Deformation and Coronary Artery Tortuosity in Patients With Hypertrophic Cardiomyopathy nanCOMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Pediatric Cardiomyopathy Mutation Analysis nanRECRUITING
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Analysis and Comparative Evaluation of Aortic Calcium by Computed Tomography and Histopathology in Patients With Aortic Stenosis nanCOMPLETED
Human Epilepsy Genetics--Neuronal Migration Disorders Study nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a CCT8 binder may also engage these)

ProteinNameSimilarity
Q4R5J0 1.000 Q4R5J0 →
Q5RAP1 1.000 Q5RAP1 →
Q3ZCI9 1.000 Q3ZCI9 →
Q6EE31 1.000 Q6EE31 →
P42932 0.998 P42932 →
Q3ZBH0 0.980 Q3ZBH0 →
P80314 0.979 P80314 →
CCT2 T-complex protein 1 subunit beta 0.975 landscape →
Q4R6F8 0.975 Q4R6F8 →
Q5XIM9 0.974 Q5XIM9 →
Q41141 0.955 Q41141 →
P21343 0.954 P21343 →
Q80Z29 0.954 Q80Z29 →
Q8W4M5 0.953 Q8W4M5 →
Q5SWU9 0.952 Q5SWU9 →
P11497 0.952 P11497 →
P11029 0.952 P11029 →
ACACA Acetyl-CoA carboxylase 1 0.950 landscape →
Q2QZ86 0.950 Q2QZ86 →
Q5R5F8 0.949 Q5R5F8 →
O80526 0.949 O80526 →
A2VE01 0.948 A2VE01 →
P35615 0.948 P35615 →
Q2QNG7 0.948 Q2QNG7 →
Q4R4U1 0.948 Q4R4U1 →
Q9SGY2 0.948 Q9SGY2 →
Q2RAK2 0.948 Q2RAK2 →
Q9TTS3 0.947 Q9TTS3 →
Q9NVE7 0.947 Q9NVE7 →
Q28559 0.946 Q28559 →