CMKLR2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL5921681	0.81	1/20
SCHEMBL5921685	0.81	1/20
SCHEMBL1123379	0.77	1/20
SCHEMBL1122810	0.75	1/20
SCHEMBL1123644	0.75	1/20
SCHEMBL1123646	0.75	1/20
SCHEMBL1122680	0.72	1/20
SCHEMBL1123316	0.71	1/20
SCHEMBL1123605	0.71	1/20
SCHEMBL2229201	0.68	1/20
SCHEMBL3497405	0.68	1/20
SCHEMBL10659411	0.68	1/20
SCHEMBL1122807	0.67	1/20
SCHEMBL1123130	0.66	1/20
SCHEMBL5921710	0.66	1/20
SCHEMBL5921717	0.66	1/20
SCHEMBL1122875	0.64	1/20
SCHEMBL4173706	0.64	1/20
SCHEMBL1122978	0.64	1/20
SCHEMBL1123407	0.64	1/20

Clinical trials — most relevant to CMKLR2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Biomarker Study of PDR001 in Combination With MCS110 in Gastric Cancer	PHASE2	UNKNOWN
Effects of Maraviroc (MVC) on HIV-related Kaposi's Sarcoma (KS)	PHASE2	COMPLETED
Efficacy of Amlexanox vs. Placebo in Type 2 Diabetic Patients	PHASE2	COMPLETED
Safety and Efficacy Study of Intravenous Immunoglobulin to Treat Japanese Encephalitis	PHASE2	COMPLETED
A Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of Subcutaneous AGX-201 for Migraine Prophylaxis	PHASE2	UNKNOWN
A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)	PHASE1	RECRUITING
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation	PHASE1	RECRUITING
Circular RNA and Chemerin in Breast Cancer Patient	nan	UNKNOWN
Chemerin, Fetuin-A, IL-34 and IL-13 Levels in Diabetic Periodontitis Patients	nan	COMPLETED
Association of Circulating Chemerin Levels and Arterial Stiffness	nan	UNKNOWN
Cytokine Expression During Radiation for Breast Cancer	nan	COMPLETED
Inflammatory Biomarkers in Psychogenic Non-epileptic Seizure	nan	UNKNOWN
Meteorin-like Levels in Individuals With Periodontitis	nan	COMPLETED
Chemerin and IL-6 Levels in Diabetes and Periodontitis	nan	COMPLETED
Inflammatory Biomarkers in Seizure	nan	UNKNOWN
The Effects of Sleeve Gastrectomy on Fractalkine	nan	COMPLETED
Assessment of the TGF-beta Pathway and Micro-RNA in Pediatric Pulmonary Arterial Hypertension	nan	UNKNOWN
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies	nan	UNKNOWN
Value of Various Chemokines in the Detection and Follow up of RCC	nan	UNKNOWN
Lung-Resident Memory Th2 Cells in Asthma	nan	ACTIVE_NOT_RECRUITING
Understanding Immunotherapy Resistance Mechanisms in Advanced Melanoma	nan	COMPLETED
Adipocytokines in Endometrial Cancer	nan	COMPLETED
C-X-C Chemokine Receptor 4 in Chronic Lymphocytic Leukemia	nan	UNKNOWN
FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation	nan	UNKNOWN
for Adipose Tissue DIabetes VAriants (fATDIVA)	nan	COMPLETED
Searching for Novel Therapeutic Approaches in Migraine Patients Resistant to Treatments	nan	RECRUITING
Use of Transcranial Magnetic Stimulation in the Post-Operative Cognitive Dysfunction in Elderly	nan	RECRUITING
The Role of Visfatin in Obesity and Periodontal Disease	nan	COMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish)	nan	UNKNOWN
Assessment of Serum CD25 Level in Systemic Sclerosis Patients with or Without Interstitial Lung Disease (ILD)	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a CMKLR2 binder may also engage these)

Protein	Name	Similarity
Q95LH1	—	1.000	Q95LH1 →
P46090	—	0.999	P46090 →
O97664	—	0.996	O97664 →
Q8K087	—	0.995	Q8K087 →
Q9YGC3	—	0.989	Q9YGC3 →
Q764M9	—	0.989	Q764M9 →
Q07FZ4	—	0.988	Q07FZ4 →
Q3LSL6	—	0.988	Q3LSL6 →
P56498	—	0.988	P56498 →
Q7ZXJ7	—	0.988	Q7ZXJ7 →
CXCR4	C-X-C chemokine receptor type 4	0.988	landscape →
Q89609	—	0.988	Q89609 →
O54814	—	0.988	O54814 →
P56491	—	0.988	P56491 →
P25930	—	0.987	P25930 →
P79394	—	0.987	P79394 →
Q3SXG2	—	0.987	Q3SXG2 →
P35373	—	0.987	P35373 →
Q8HZU0	—	0.987	Q8HZU0 →
Q7YS92	—	0.987	Q7YS92 →
Q9TSQ8	—	0.986	Q9TSQ8 →
P32303	—	0.986	P32303 →
Q8HZU1	—	0.986	Q8HZU1 →
P35411	—	0.986	P35411 →
P79785	—	0.986	P79785 →
Q28474	—	0.986	Q28474 →
P61072	—	0.986	P61072 →
P69333	—	0.985	P69333 →
P69332	—	0.985	P69332 →
P51676	—	0.985	P51676 →