COPS6

COP9 signalosome complex subunit 6 · Q7L5N1 · COPS6 on Sugi Atlas →

0 patent compounds predicted against COPS6, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to COPS6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome PHASE3COMPLETED
Addition of Everolimus to Standard of Care in Carcinoma Gallbladder PHASE2/PHASE3RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN
MEHMO Natural History and Biomarkers nanRECRUITING
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Monogenic Diabetes Misdiagnosed as Type 1 nanRECRUITING
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis nanCOMPLETED
Implementation of Molecular Diagnostic Pathways nanUNKNOWN
Gene Analysis of Parkinson's Disease nanCOMPLETED
Phenotype/Genotype Correlations in Neuromuscular Disorders nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Inherited Reproductive Disorders nanRECRUITING
Child Development and Genetic Biomarkers(II): Gene Verification and Data Integration nanUNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Multidisciplinary Evaluation and a Genome-wide Analysis in a Cohort of Idiopathic Short Stature Patients nanRECRUITING
Genetic Investigation of Cancer Predisposition nanNOT_YET_RECRUITING
Study of Constitutional Platelet Disease nanUNKNOWN
Study of Proteus Syndrome and Related Congenital Disorders nanRECRUITING
Use of miRNAs in Growth Hormone Deficiency (GHD) nanUNKNOWN
Study of The Association of Mutations in The NPHS2 Gene and Nephrotic Syndrome in Children and Adults in Middle East nanUNKNOWN
Identification of the Genetic Causes of Rare Diseases With Negative Exome Findings nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a COPS6 binder may also engage these)

ProteinNameSimilarity
O88545 1.000 O88545 →
Q5REY0 1.000 Q5REY0 →
A6QQ21 1.000 A6QQ21 →
A7TX81 1.000 A7TX81 →
Q07G98 0.990 Q07G98 →
Q6NUC2 0.989 Q6NUC2 →
Q5R5F8 0.963 Q5R5F8 →
Q9NVE7 0.961 Q9NVE7 →
Q4R4U1 0.961 Q4R4U1 →
Q2KJ46 0.961 Q2KJ46 →
Q7Z3J2 0.961 Q7Z3J2 →
P11029 0.960 P11029 →
Q5ZLA5 0.959 Q5ZLA5 →
PSMD3 26S proteasome non-ATPase regulatory subunit 3 0.959 landscape →
Q5SWU9 0.958 Q5SWU9 →
Q6P6Q9 0.958 Q6P6Q9 →
ACACA Acetyl-CoA carboxylase 1 0.957 landscape →
Q9BPX6 0.957 Q9BPX6 →
Q32KL5 0.956 Q32KL5 →
B1H2N3 0.955 B1H2N3 →
Q10568 0.955 Q10568 →
Q0VCL3 0.955 Q0VCL3 →
P14685 0.954 P14685 →
P11497 0.954 P11497 →
RPTOR Regulatory-associated protein of mTOR 0.954 landscape →
Q9P2I0 0.954 Q9P2I0 →
Q6P7L9 0.954 Q6P7L9 →
AP2A1 AP-2 complex subunit alpha-1 0.954 landscape →
Q641X8 0.954 Q641X8 →
Q08E27 0.954 Q08E27 →