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IQGAP1

Ras GTPase-activating-like protein IQGAP1 · P46940 · IQGAP1 on Sugi Atlas →

0 patent compounds predicted against IQGAP1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to IQGAP1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas PHASE2COMPLETED
Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1 PHASE2COMPLETED
FAK Inhibitor in Patients With Advanced Solid Tumors PHASE1NOT_YET_RECRUITING
Genetics and Psychopathology in the 22q11 Deletion Syndrome nanUNKNOWN
Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial nanRECRUITING
Genetic Markers and Biomarkers in Patients With Intellectual Disabilities of Genetic Origin nanRECRUITING
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Prospective Validation of a DNA Damage Repair-Hippo Pathway Signature in Patients With Advanced Gastric Cancer nanUNKNOWN
ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients nanCOMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Molecular Diagnosis of Syndromic or Isolated Severe Intellectual Disability Using Whole Exome Sequencing : a Pilot Study nanCOMPLETED
Genetic Identification (ID) of Segmental Dysplastic Nevi nanWITHDRAWN
Brain Control of Movements in Cerebral Palsy nanCOMPLETED
Research and Characterization of New Genes Involved in Intellectual Disability nanCOMPLETED
Analysis of Genomic DNA Alterations in Familial Schizophrenia nanUNKNOWN
Corpus Callosum Agenesis and Intellectual Disability nanCOMPLETED
Clinical Phenotyping and Characterization of Neural Networks and Cognitive Processes Involved in Mental Retardation X-linked nanUNKNOWN
Inter-regional Project of the Great Western Exploration Approach for Exome Molecular Causes Severe Intellectual Disability Isolated or Syndromic nanCOMPLETED
Genetic Analysis of Familial Melanoma nanCOMPLETED
Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies nanRECRUITING
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
Human Epilepsy Genetics--Neuronal Migration Disorders Study nanRECRUITING
Chromosome 5Q Gene Variants and Asthma-Related Traits nanCOMPLETED
Long QT Syndrome-Population Genetics and Cardiac Studies nanCOMPLETED
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus nanACTIVE_NOT_RECRUITING
Genetic Variants Associated With the Risk of Gall Stones and Cirrhosis. nanNOT_YET_RECRUITING
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte nanCOMPLETED
Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles nanACTIVE_NOT_RECRUITING
A Family Study of Copy Number Variations in Patients With Autism Spectrum Disorder nanCOMPLETED
Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a IQGAP1 binder may also engage these)

ProteinNameSimilarity
Q9JKF1 — 1.000 Q9JKF1 →
Q3UQ44 — 0.978 Q3UQ44 →
Q13576 — 0.978 Q13576 →
EIF3A Eukaryotic translation initiation factor 3 subunit A 0.975 landscape →
P23116 — 0.973 P23116 →
Q1JU68 — 0.973 Q1JU68 →
Q6PCR7 — 0.971 Q6PCR7 →
Q08043 — 0.969 Q08043 →
A2VD00 — 0.969 A2VD00 →
A4II09 — 0.968 A4II09 →
O88990 — 0.968 O88990 →
Q6P4T2 — 0.968 Q6P4T2 →
SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 0.968 landscape →
P57780 — 0.967 P57780 →
Q5RCS6 — 0.967 Q5RCS6 →
A5D7D1 — 0.967 A5D7D1 →
Q90734 — 0.967 Q90734 →
A2AT37 — 0.967 A2AT37 →
O00291 — 0.967 O00291 →
Q8CHV6 — 0.967 Q8CHV6 →
Q6AYE3 — 0.966 Q6AYE3 →
GTF3C3 General transcription factor 3C polypeptide 3 0.966 landscape →
ACTN4 Alpha-actinin-4 0.966 landscape →
Q80ZD1 — 0.966 Q80ZD1 →
Q3B7N2 — 0.966 Q3B7N2 →
E9Q4Z2 — 0.966 E9Q4Z2 →
Q5R416 — 0.966 Q5R416 →
Q2PFV7 — 0.966 Q2PFV7 →
Q5R882 — 0.966 Q5R882 →
Q9QXQ0 — 0.965 Q9QXQ0 →