KIF15 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL5777929	0.78	2/20
SCHEMBL5777933	0.78	2/20
SCHEMBL1394836	0.64	2/20
SCHEMBL1394837	0.64	2/20
SCHEMBL1394700	0.61	2/20
SCHEMBL5080490	0.61	2/20
SCHEMBL5367150	0.61	2/20
SCHEMBL1395085	0.58	2/20
SCHEMBL1395087	0.58	2/20
SCHEMBL1394840	0.57	2/20
SCHEMBL5083387	0.57	2/20
SCHEMBL5774559	0.57	2/20
SCHEMBL5774564	0.57	2/20
SCHEMBL5777676	0.56	2/20
SCHEMBL5777681	0.56	2/20
SCHEMBL5778246	0.56	2/20
SCHEMBL5778252	0.56	2/20
SCHEMBL5773452	0.55	2/20
SCHEMBL5773456	0.55	2/20
SCHEMBL5773208	0.54	2/20

Clinical trials — most relevant to KIF15 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy With GenSci122 in Participants With Advanced Solid Tumors	PHASE1	RECRUITING
Study of ABT-751 in Patients With Refractory Hematologic Malignancies	PHASE1	COMPLETED
Safety Study of Peptide Cancer Vaccine To Treat HLA-A*24-positive Advanced Small Cell Lung Cancer	PHASE1	COMPLETED
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype	EARLY_PHASE1	COMPLETED
Study of Modified Atkins Diet in Kabuki Syndrome	EARLY_PHASE1	COMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
Registry and Natural History of Epilepsy-Dyskinesia Syndromes	nan	RECRUITING
Importance of the Microtubule Cytoskeleton in Oocyte Competence	nan	COMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
The Relation of Microtubule-Associated Protein 2 and Cell Migration	nan	UNKNOWN
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy	nan	COMPLETED
Biomarker Research in Inherited Movement Disorders	nan	RECRUITING
Integrated Model for Promoting Parenting and Early School Readiness in Pediatrics	nan	COMPLETED
Better Delineation of CDK13 Related Phenotype and Epigenetic Signature.	nan	UNKNOWN
Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F	nan	ACTIVE_NOT_RECRUITING
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others	nan	RECRUITING
PCD New Gene Discovery	nan	COMPLETED
Evaluation and Treatment of Pediatric, Developmental, and Genetic Eye Diseases	nan	COMPLETED
A Natural History Study of Neuronal Ceroid Lipofuscinosis Type 5 (CLN5)	nan	COMPLETED
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome	nan	RECRUITING
A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes	nan	RECRUITING
Natural History, Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic Disease	nan	RECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
Diagnosis of Primary Ciliary Dyskinesia	nan	COMPLETED
Exploring a Motor Learning Technique Based on the Mirror Motor Neuron System	nan	COMPLETED
Enhanced Linkage Maps From Family-Based Genetics Studies	nan	COMPLETED
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders	nan	COMPLETED
Hong Kong Spinocerebellar Ataxias Registry	nan	RECRUITING
Gait in Rare Diseases	nan	COMPLETED
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a KIF15 binder may also engage these)

Protein	Name	Similarity
Q91785	—	1.000	Q91785 →
Q6P9L6	—	1.000	Q6P9L6 →
Q498L9	—	1.000	Q498L9 →
Q86VH2	—	1.000	Q86VH2 →
Q90640	—	1.000	Q90640 →
Q7TSP2	—	1.000	Q7TSP2 →
Q2VIQ3	—	1.000	Q2VIQ3 →
F4IIS5	—	1.000	F4IIS5 →
P56536	—	1.000	P56536 →
KIF5C	Kinesin heavy chain isoform 5C	1.000	landscape →
P28738	—	1.000	P28738 →
P21613	—	1.000	P21613 →
Q8GS71	—	0.999	Q8GS71 →
Q5R9K7	—	0.999	Q5R9K7 →
Q2PQA9	—	0.999	Q2PQA9 →
P33174	—	0.999	P33174 →
F4IJK6	—	0.998	F4IJK6 →
KIF5B	Kinesin-1 heavy chain	0.998	landscape →
O23826	—	0.998	O23826 →
KIF5A	Kinesin heavy chain isoform 5A	0.998	landscape →
P17210	—	0.998	P17210 →
Q6RT24	—	0.998	Q6RT24 →
Q7Z4S6	—	0.998	Q7Z4S6 →
Q9LZU5	—	0.997	Q9LZU5 →
Q9S7P3	—	0.997	Q9S7P3 →
Q8J1G7	—	0.997	Q8J1G7 →
B9F2Y7	—	0.997	B9F2Y7 →
P35978	—	0.997	P35978 →
P46863	—	0.997	P46863 →
Q91784	—	0.997	Q91784 →