LENG8

Leukocyte receptor cluster member 8 · Q96PV6 · LENG8 on Sugi Atlas →

0 patent compounds predicted against LENG8, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to LENG8 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Interferon Gamma to Treat Leukocyte Adhesion Deficiency Type I PHASE2COMPLETED
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Esophageal Cancer PHASE1/PHASE2COMPLETED
Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency PHASE2ACTIVE_NOT_RECRUITING
Safety and Efficacy of Tag-7 Gene-modified Vaccine in Locally Advanced or Metastatic Malignant Melanoma or Kidney Cancer PHASE1/PHASE2COMPLETED
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Gastric Cancer PHASE1/PHASE2COMPLETED
Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease PHASE2ACTIVE_NOT_RECRUITING
DEPLETHINK - LymphoDEPLEtion and THerapeutic Immunotherapy With NKR-2 PHASE1/PHASE2COMPLETED
T-cells Expressing an Anti-SLAMF7 CAR for Treating Multiple Myeloma PHASE1COMPLETED
A Gene Therapy Trial to Evaluate the Safety and Efficacy of RP-L201 in Subjects With Leukocyte Adhesion Deficiency-I PHASE1WITHDRAWN
Safety Study of Multiple Peptide Vaccine to Esophageal Cancer PHASE1COMPLETED
Clinical Study of CLL1 CAR-T Cells in the Treatment of Hematological Malignancies EARLY_PHASE1UNKNOWN
Role of LILRA3 in Ankylosing Spondylitis and Axial Psoriatic Patients nanUNKNOWN
TIGIT in Patients With Chronic Myeloid Leukemia nanUNKNOWN
The Role of Programmed Death Ligand -1 (Pdl-1) in Lung Cancer nanCOMPLETED
Interleukin-8 Level in Packed Red Blood Cells nanNOT_YET_RECRUITING
Circular RNA and Chemerin in Breast Cancer Patient nanUNKNOWN
Effect of Mepolizumab on Severe Eosinophilic Asthma nanUNKNOWN
Immune Checkpoints in Predicting Response to Neoadjuvant Therapy in Rectal Cancer nanCOMPLETED
Pharmacogenomics of Interferon and Ribavirin Treatment in Patients With Chronic Hepatitis C Virus Infection nanUNKNOWN
Clinical Application of PET Imaging Targeting GPA33 in Malignant Tumors nanNOT_YET_RECRUITING
Expression of CD19 Complex in Lymphoproliferative Disorders nanUNKNOWN
Implication of CCR4-NOT Complex Subunit 7 Expression in Natural Killer Cell Resistance in Metastatic Breast Cancer nanCOMPLETED
Inflammation Genomics and Atherosclerosis - Ancillary to CARDIA nanCOMPLETED
S9031-S9126-S9333-S9500-A, Studying Bone Marrow and Blood Samples From Patients With Acute Myeloid Leukemia nanCOMPLETED
The Role of Neutrophil CD64 and Soluble Triggering Receptor Expressed on Myeloid Cells 1 in Neonatal Sepsis nanUNKNOWN
Characterization of NK Cells Under First Line Advanced Therapy Either as Curative Therapy for Metastatic Melanoma or as Adjuvant Therapy for High-risk of Recurrence nanUNKNOWN
Differential Expression of CD200 in B-chronic Lymphoproliferative Disorders by Multicolour Flow Cytometry nanUNKNOWN
Assessment of Natural Killer Cells in Unexplained Recurrent Pregnancy Loss nanUNKNOWN
Effect of Periodontal Treatment on Inflammasome Proteins in Periodontal Diseases nanUNKNOWN
Role of CD11a in Pathogenesis of Primary ITP and Effect of Immunosuppressive Therapy on Its Level nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a LENG8 binder may also engage these)

ProteinNameSimilarity
Q8CBY3 1.000 Q8CBY3 →
Q32NW2 0.996 Q32NW2 →
A4QNR8 0.992 A4QNR8 →
O75061 0.987 O75061 →
Q27974 0.987 Q27974 →
Q8CHU3 0.986 Q8CHU3 →
NFRKB Nuclear factor related to kappa-B-binding protein 0.986 landscape →
Q63618 0.986 Q63618 →
Q32N92 0.986 Q32N92 →
Q9Z1Z3 0.986 Q9Z1Z3 →
Q08E13 0.986 Q08E13 →
Q4V882 0.986 Q4V882 →
F4IUY8 0.985 F4IUY8 →
Q5PRF9 0.985 Q5PRF9 →
O95208 0.985 O95208 →
O88339 0.985 O88339 →
Q9ERA6 0.984 Q9ERA6 →
Q9H201 0.984 Q9H201 →
Q5RIX9 0.984 Q5RIX9 →
Q80TZ3 0.984 Q80TZ3 →
Q29RR5 0.984 Q29RR5 →
Q8CH02 0.984 Q8CH02 →
Q8IWZ8 0.983 Q8IWZ8 →
Q6EE22 0.983 Q6EE22 →
Q80XS6 0.983 Q80XS6 →
Q9Y103 0.983 Q9Y103 →
Q3U1N2 0.983 Q3U1N2 →
EPN1 Epsin-1 0.983 landscape →
Q6PGA0 0.983 Q6PGA0 →
RNF10 E3 ubiquitin-protein ligase RNF10 0.983 landscape →