Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.85 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | GSR | P00390 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7880398 | 0.87 | MEN1 (0.79) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL7869225 | 0.84 | MBNL1 (0.81) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL18163841 | 0.83 | ADORA2A (0.80) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL20087053 | 0.83 | MBNL1 (0.80) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL20087077 | 0.83 | MBNL1 (0.80) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL20087027 | 0.83 | MBNL1 (0.80) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL7875793 | 0.83 | ADORA2A (0.83) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL29375789 | 0.83 | ADORA2A (0.83) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL23795497 | 0.82 | MBNL1 (0.75) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL12057934 | 0.82 | ADORA2A (0.78) | MBNL1MEN1KMT2ATDP1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382215-B2 | Therapeutic methods and agents for treating myotonic dystrophy | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-07-05 | — | — | US | disclosed |
| US-20140288080-A1 | THERAPEUTIC METHODS AND AGENTS FOR TREATING MYOTONIC DYSTROPHY | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288080-A1 | THERAPEUTIC METHODS AND AGENTS FOR TREATING MYOTONIC DYSTROPHY | POLRMT, SMN1; SMN2, MTPN | MBNL1 10/4885MEN1 3548/4885KMT2A 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.