MYH9 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL4330339	1.00	1/20
SCHEMBL4330341	1.00	1/20
SCHEMBL15919292	1.00	1/20
SCHEMBL29354793	1.00	1/20
SCHEMBL29438548	1.00	1/20
SCHEMBL30075966	1.00	1/20
SCHEMBL23235584	0.85	1/20
SCHEMBL23909200	0.85	1/20
SCHEMBL21067621	0.83	1/20
SCHEMBL23909208	0.82	1/20
SCHEMBL23909209	0.82	1/20
SCHEMBL19183407	0.81	1/20
SCHEMBL19200636	0.81	1/20
SCHEMBL22512479	0.81	1/20
SCHEMBL31218583	0.81	1/20
SCHEMBL19183119	0.80	1/20
SCHEMBL19183427	0.80	1/20
SCHEMBL19200581	0.80	1/20
SCHEMBL29695452	0.80	1/20
SCHEMBL29695517	0.80	1/20

Clinical trials — most relevant to MYH9 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Treatment of Preclinical Hypertrophic Cardiomyopathy With Diltiazem	PHASE2/PHASE3	COMPLETED
The TRansendocardial Stem Cell Injection Delivery Effects on Neomyogenesis STudy (The TRIDENT Study)	PHASE2	COMPLETED
Evaluating MED2005 & Nitrostat Bioavailability	PHASE1	COMPLETED
Phenotypic and Genotypic Identification and Characterization of MYH9-related Constitutional Thrombocytopenia	nan	COMPLETED
Mapping of End Stage Renal Disease Genetic Susceptibility in African Americans by Admixture Linkage Disequilibrium	nan	COMPLETED
Evaluation of Albuminuria HIV-Infected Patients	nan	COMPLETED
Genetic Markers for Focal Segmental Glomerulosclerosis	nan	COMPLETED
Transcutaneous Functional Magnetic Muscle Stimulation in Critically Ill	nan	UNKNOWN
Genes Mutation Pentalogy of Cantrell	nan	WITHDRAWN
Natural History Study for Patients With Nemaline Myopathy in Belgium	nan	NOT_YET_RECRUITING
Pediatric Cardiomyopathy Mutation Analysis	nan	RECRUITING
LIPCAR, Cuproptosis, and Α-SMA in the Pathogenesis of AMI and Remodeling	nan	NOT_YET_RECRUITING
FASHION Fabry Disease Hypertrophic Cardiomyopathy and Infammation	nan	UNKNOWN
Characteristics of Nondystrophic Myotonias	nan	COMPLETED
Phenotype - Genotype Correlation in a Sample of Egyptian Patients With Congenital Myopathies and Congenital Muscular Dystrophies	nan	RECRUITING
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease	nan	COMPLETED
WiTNNess - TNNT1 Myopathy Natural History Study	nan	RECRUITING
Congenital Muscle Disease Study of Patient and Family Reported Medical Information	nan	RECRUITING
Registry of Unexplained Cardiac Arrest	nan	COMPLETED
Precision Medicine for Nociception, Sngception and Proprioception.	nan	RECRUITING
Role of Ultrasound in Diagnosis of Muscle Diseases	nan	COMPLETED
Heart and Skeletal Muscle Problems in Neuroacanthocytosis	nan	COMPLETED
Chronic Muscle Disuse in the Elderly	nan	COMPLETED
Precision Pharmacogenetics and Genotype Class Based Prediction of Mavacamten Response in Obstructive Hypertrophic Cardiomyopathy	nan	NOT_YET_RECRUITING
Acquirement of Clinical and Genomic Data to Diagnose in Rare Inherited Cardiomyopathy	nan	RECRUITING
The Role of Biomarkers in Inherited Cardiac Conditions	nan	WITHDRAWN
Molecular and Genetic Studies of Congenital Myopathies	nan	RECRUITING
New Diagnostic Strategy in Hypertrophic Cardiomyopathy	nan	UNKNOWN
Genetic Analysis of Familial Hypertrophic Cardiomyopathy	nan	COMPLETED
Hypertrophic Cardiomyopathy Registry, Biobank and Imaging Data Repository	nan	ENROLLING_BY_INVITATION

Related proteins — ESM-2 sequence neighbours (a MYH9 binder may also engage these)

Protein	Name	Similarity
Q258K2	—	1.000	Q258K2 →
P14105	—	1.000	P14105 →
Q8VDD5	—	1.000	Q8VDD5 →
P35749	—	1.000	P35749 →
Q9JLT0	—	1.000	Q9JLT0 →
O08638	—	1.000	O08638 →
P10587	—	1.000	P10587 →
MYH10	Myosin-10	1.000	landscape →
Q62812	—	1.000	Q62812 →
Q27991	—	1.000	Q27991 →
P35748	—	1.000	P35748 →
Q61879	—	0.998	Q61879 →
P02564	—	0.996	P02564 →
P49824	—	0.995	P49824 →
Q9BE39	—	0.995	Q9BE39 →
P13533	—	0.994	P13533 →
Q9TV62	—	0.994	Q9TV62 →
Q8MJV1	—	0.994	Q8MJV1 →
Q9TV63	—	0.993	Q9TV63 →
P12883	—	0.993	P12883 →
P13540	—	0.992	P13540 →
P79293	—	0.992	P79293 →
Q076A6	—	0.992	Q076A6 →
Q076A7	—	0.992	Q076A7 →
Q9BE40	—	0.992	Q9BE40 →
Q9TV61	—	0.992	Q9TV61 →
P13538	—	0.991	P13538 →
Q9BE41	—	0.991	Q9BE41 →
P12882	—	0.991	P12882 →
P11055	—	0.991	P11055 →