SCHEMBL29438548

SCHEMBL29438548

Cc1ccc2c(c1)C(=O)[C@]1(O)CCN(c3ccccc3)C1=N2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
MAPT P10636 4/20 1.00
KDM4E B2RXH2 4/20 1.00
CYP3A4 P08684 2/20 1.00
CYP1A2 P05177 1/20 1.00
CYP2D6 P10635 1/20 1.00
CYP2C9 P11712 1/20 1.00
CYP2C19 P33261 1/20 1.00
ALOX15 P16050 1/20 1.00
CASP1 P29466 1/20 1.00
MYH9 P35579 1/20 1.00
MYH10 P35580 1/20 1.00
CASP7 P55210 1/20 1.00
HBB P68871 1/20 1.00
MYH2 Q9UKX2 1/20 0.62
METAP2 P50579 8/20 0.42
HSD11B1 P28845 1/20 0.37
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4330341 1.00 MEN1 (1.00) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL4330339 1.00 MEN1 (1.00) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL29354793 1.00 MEN1 (1.00) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL30075966 1.00 MEN1 (1.00) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL15919292 1.00 MEN1 (1.00) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL23909200 0.92 MEN1 (0.85) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL23235584 0.92 MEN1 (0.85) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL21067621 0.91 MEN1 (0.83) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL23909209 0.90 MEN1 (0.82) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL23909208 0.90 MEN1 (0.82) MEN1KMT2AMAPTKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118931833-A Method for obtaining platelets by inducing iPSC differentiation 呈诺再生医学科技(北京)有限公司 2024-11-12 CN claimed
CN-115873797-B Amplification culture medium and culture method for retinal pigment epithelial cells 北京干细胞与再生医学研究院 2024-08-13 CN claimed
US-11622964-B2 Method for destroying cellular mechanical homeostasis and promoting regeneration and repair of tissues and organs, and use thereof INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES (CN) 2023-04-11 US claimed
CN-111778205-B Human cardiac muscle cell separation reagent, culture medium, separation method and culture method 青岛百洋智心科技有限公司 2022-09-30 CN claimed
CN-111405898-B Method for destroying cell mechanical homeostasis and promoting tissue and organ regeneration and repair and application thereof 中国科学院动物研究所 2022-09-13 CN claimed
CN-114807034-A Preparation method of Muller cells derived from human pluripotent stem cells 中山大学中山眼科中心 2022-07-29 CN claimed
CN-113234670-B Separation and culture method of adult mouse atrial myocytes 西安交通大学 2022-07-12 CN claimed
US-20220213444-A1 COMPOSITIONS AND METHODS FOR CELLULAR REPROGRAMMING CHILDRENS HOSPITAL MED CT (US) 2022-07-07 US claimed
CN-114369572-A Composition and method for transdifferentiating non-neuronal cells into neurons 中国科学院动物研究所 2022-04-19 CN claimed
EP-3976767-A1 COMPOSITIONS AND METHODS FOR CELLULAR REPROGRAMMING Children's Hospital Medical Center, Center for Technology Commercialization (US) 2022-04-06 EP claimed
CN-114207119-A Compositions and methods for reprogramming of cells 儿童医院医学中心 2022-03-18 CN claimed
US-20250341512-A1 HIGH-THROUGHPUT AUTOMATION OF ORGANOIDS FOR IDENTIFYING THERAPEUTIC STRATEGIES UNIVERSITY OF WASHINGTON (US) 2025-11-06 US disclosed
US-20250333708-A1 MANIPULATING NEPHRON DIFFERENTIATION RATE IN INDUCED HUMAN PLURIPOTENT STEM CELL ORGANOIDS AND TISSUES BY ENGINEERING MECHANICS OF THE MICROENVIRONMENT UNIV PENNSYLVANIA (US) 2025-10-30 US disclosed
EP-4627085-A1 LONG NON-CODING RNA LIPTER PRESERVES LIPID METABOLISM OF THE HUMAN HEART The Trustees of Indiana University (US) 2025-10-08 EP disclosed
US-12421243-B2 Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms PRINTNET KERESKEDELMI ÉS SZOLGÁLTATÓ KFT. (HU) 2025-09-23 US disclosed
CN-114369572-A Composition and method for transdifferentiating non-neuronal cells into neurons 中国科学院动物研究所 2022-04-19 CN disclosed
EP-3976767-A1 COMPOSITIONS AND METHODS FOR CELLULAR REPROGRAMMING Children's Hospital Medical Center, Center for Technology Commercialization (US) 2022-04-06 EP disclosed
CN-114207119-A Compositions and methods for reprogramming of cells 儿童医院医学中心 2022-03-18 CN disclosed
EP-3967751-A1 HUMAN CARDIOMYOCYTE SEPARATION REAGENT, CULTURE MEDIUM, SEPARATION METHOD, AND CULTURE METHOD Fuwai Hospital of Chinese Academy of Medical Sciences (CN) 2022-03-16 EP disclosed
WO-2022037570-A1 EXPANSION CULTURE MEDIUM AND CULTURE METHOD FOR NEURAL CELLS 中国科学院动物研究所 2022-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11622964-B2 Method for destroying cellular mechanical homeostasis and promoting regeneration and repair of tissues and organs, and use thereof MYLK2, MYLK, MYLK3 MEN1 2498/4885KMT2A 3509/4885MAPT 4727/4885
US-12421243-B2 Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms MYH2, MYLK2, MYO1B MEN1 2122/4885KMT2A 3113/4885MAPT 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.