NAA10 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to NAA10 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS	PHASE2	COMPLETED
An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab	PHASE1/PHASE2	RECRUITING
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma	PHASE1/PHASE2	COMPLETED
NAD Supplementation to Prevent Progressive Neurological Disease in Ataxia Telangiectasia	PHASE2	ACTIVE_NOT_RECRUITING
Search for Genes Influencing Childhood Absence Epilepsy (CAE) Study	nan	COMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants.	nan	UNKNOWN
Biomarker Research in Inherited Movement Disorders	nan	RECRUITING
Thermogenic Silencer Regulatory Factors in Humans	nan	ACTIVE_NOT_RECRUITING
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan	nan	ENROLLING_BY_INVITATION
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders	nan	COMPLETED
Identification of New FTLD Genes	nan	UNKNOWN
Lipa Gene Mutation in PED-LIPIGEN (Pediatric FH Subjects)	nan	UNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
Southeastern ATTR Amyloidosis Consortium: SEATTRAC Family Registry	nan	NOT_YET_RECRUITING
Developing Genetic Education for Smoking Cessation	nan	COMPLETED
Genetic Analysis of Attention Deficit Hyperactivity Disorder (ADHD)	nan	COMPLETED
Molecular Studies on the Candidate Genes of Dopaminergic and Noradrenergic Systems in ADHD	nan	COMPLETED
Exploring the Genetics of Neuropathic Pain	nan	RECRUITING
Corpus Callosum Agenesis and Intellectual Disability	nan	COMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients	nan	RECRUITING
Genetic Study of Familial Epilepsy	nan	COMPLETED
Blood Sample Donations to Study the Role of Genes in Pain	nan	COMPLETED
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte	nan	COMPLETED
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes	nan	RECRUITING
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Target of Suv420h1/2 in Hepatocytes	nan	RECRUITING
Effect of Exercise Gene Expression and Histone Modifications in Patients With Hemiplegia	nan	RECRUITING
Microarray Analysis in Syndromic Obesity	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a NAA10 binder may also engage these)

Protein	Name	Similarity
Q9QY36	—	1.000	Q9QY36 →
Q2KI14	—	1.000	Q2KI14 →
Q9BSU3	—	0.997	Q9BSU3 →
Q3UX61	—	0.990	Q3UX61 →
Q4V8K3	—	0.980	Q4V8K3 →
Q4W5Z4	—	0.944	Q4W5Z4 →
DNMT3A	DNA (cytosine-5)-methyltransferase 3A	0.944	landscape →
Q1LZ53	—	0.939	Q1LZ53 →
O88508	—	0.938	O88508 →
O13016	—	0.931	O13016 →
PTPN1	Tyrosine-protein phosphatase non-receptor type 1	0.931	landscape →
KCNAB1	Voltage-gated potassium channel subunit beta-1	0.926	landscape →
Q9XT31	—	0.923	Q9XT31 →
P20417	—	0.920	P20417 →
D3Z7P3	—	0.916	D3Z7P3 →
GLS	Glutaminase kidney isoform, mitochondrial	0.911	landscape →
Q7RTP6	—	0.911	Q7RTP6 →
P35821	—	0.910	P35821 →
Q9DFS6	—	0.910	Q9DFS6 →
P13264	—	0.909	P13264 →
P48597	—	0.909	P48597 →
A0A2R8QFQ6	—	0.908	A0A2R8QFQ6 →
WDR26	WD repeat-containing protein 26	0.908	landscape →
Q28528	—	0.908	Q28528 →
D1LYT2	—	0.907	D1LYT2 →
Q5SRY7	—	0.906	Q5SRY7 →
Q9N0T5	—	0.906	Q9N0T5 →
GABRB2	Gamma-aminobutyric acid receptor subunit beta-2	0.905	landscape →
P15431	—	0.905	P15431 →
Q8CJ19	—	0.905	Q8CJ19 →