NDUFA12

NADH dehydrogenase [ubiquinone] 1 alpha subco · Q9UI09 · NDUFA12 on Sugi Atlas →

622 patent compounds predicted against NDUFA12, 358 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL15258558	0.76	8/20
R-(+)-Marmin (SCHEMBL27804600)	0.83	7/20
R-(+)-Marmin (SCHEMBL29353819)	0.83	7/20
R-(+)-Marmin (SCHEMBL29625637)	0.83	7/20
SCHEMBL12362713	0.77	7/20
SCHEMBL15080621	0.77	7/20
SCHEMBL12362702	0.73	7/20
SCHEMBL31179835	0.59	7/20
SCHEMBL31397586	0.53	7/20
SCHEMBL31000416	0.78	6/20
SCHEMBL12362734	0.60	6/20
SCHEMBL13973668	0.47	6/20
SCHEMBL16316892	0.47	6/20
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
Umbelliprenin (SCHEMBL18265478)	0.98	5/20
Umbelliprenin (SCHEMBL26641528)	0.98	5/20
Umbelliprenin (SCHEMBL28133292)	0.98	5/20
SCHEMBL29999425	0.83	5/20
SCHEMBL24700226	0.81	5/20

Clinical trials — most relevant to NDUFA12 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease	PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Parkinson's Disease Treatment With Coenzyme Q10	PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection	nan	COMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Diagnostic Odyssey Survey 2	nan	COMPLETED
Pharmacokinetic Study on Three Formulations of Coenzyme Q10 With Different Carriers	nan	UNKNOWN
Nicotinamide Riboside in Ulcerative Colitis	nan	RECRUITING
Ccf mtDNA as a Neurodegenerative Biomarker	nan	UNKNOWN
Survey on Supplement Use in Mitochondrial Disease	nan	COMPLETED
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Q10 Ubiquinol in Autism Spectrum Disorder and in Phelan-McDermid Syndrome.	nan	UNKNOWN
Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity	nan	RECRUITING
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis	nan	COMPLETED
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a NDUFA12 binder may also engage these)

Protein	Name	Similarity
Q0MQ85	—	1.000	Q0MQ85 →
O97725	—	1.000	O97725 →
Q6CG53	—	1.000	Q6CG53 →
Q0MQ86	—	0.998	Q0MQ86 →
Q0MQ87	—	0.998	Q0MQ87 →
Q9N2W7	—	0.997	Q9N2W7 →
Q7TMF3	—	0.996	Q7TMF3 →
Q54MV7	—	0.995	Q54MV7 →
Q9M9M9	—	0.993	Q9M9M9 →
O74988	—	0.982	O74988 →
Q9ZCK4	—	0.981	Q9ZCK4 →
Q6BY05	—	0.981	Q6BY05 →
P53077	—	0.980	P53077 →
Q5R4R9	—	0.980	Q5R4R9 →
Q6FWV2	—	0.979	Q6FWV2 →
A5DT64	—	0.979	A5DT64 →
A4FUH5	—	0.978	A4FUH5 →
Q29HF1	—	0.978	Q29HF1 →
Q5A3J1	—	0.978	Q5A3J1 →
Q9W549	—	0.978	Q9W549 →
Q59J78	—	0.978	Q59J78 →
A8X871	—	0.978	A8X871 →
P53700	—	0.978	P53700 →
A8XYW9	—	0.978	A8XYW9 →
B4KN44	—	0.978	B4KN44 →
Q61JS7	—	0.977	Q61JS7 →
O74370	—	0.977	O74370 →
O60084	—	0.977	O60084 →
P91929	—	0.977	P91929 →
B4KPG8	—	0.977	B4KPG8 →