Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NDUFS8 | O00217 | 5/20 | 0.81 |
| ▸ | COXFA4 | O00483 | 5/20 | 0.81 |
| ▸ | NDUFAB1 | O14561 | 5/20 | 0.81 |
| ▸ | NDUFA1 | O15239 | 5/20 | 0.81 |
| ▸ | NDUFS4 | O43181 | 5/20 | 0.81 |
| ▸ | NDUFB5 | O43674 | 5/20 | 0.81 |
| ▸ | NDUFB3 | O43676 | 5/20 | 0.81 |
| ▸ | NDUFC1 | O43677 | 5/20 | 0.81 |
| ▸ | NDUFA2 | O43678 | 5/20 | 0.81 |
| ▸ | NDUFS5 | O43920 | 5/20 | 0.81 |
| ▸ | NDUFS7 | O75251 | 5/20 | 0.81 |
| ▸ | NDUFS2 | O75306 | 5/20 | 0.81 |
| ▸ | NDUFS6 | O75380 | 5/20 | 0.81 |
| ▸ | NDUFB1 | O75438 | 5/20 | 0.81 |
| ▸ | NDUFS3 | O75489 | 5/20 | 0.81 |
| ▸ | NDUFB6 | O95139 | 5/20 | 0.81 |
| ▸ | NDUFA3 | O95167 | 5/20 | 0.81 |
| ▸ | NDUFB4 | O95168 | 5/20 | 0.81 |
| ▸ | NDUFB8 | O95169 | 5/20 | 0.81 |
| ▸ | NDUFB2 | O95178 | 5/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29999425 | 0.89 | NDUFS8 (0.83) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| Auraptene SCHEMBL2535034 | 0.89 | ALOX15 (1.00) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| Auraptene SCHEMBL2535029 | 0.89 | ALOX15 (1.00) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| Umbelliprenin SCHEMBL26641528 | 0.88 | ALOX15 (1.00) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| Umbelliprenin SCHEMBL18265478 | 0.88 | ALOX15 (1.00) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| Umbelliprenin SCHEMBL28133292 | 0.88 | ALOX15 (1.00) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL18265492 | 0.84 | KDM4E (0.78) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| 7-Prenyloxycoumarin SCHEMBL4898255 | 0.82 | KDM4E (1.00) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL17898120 | 0.81 | ALOX15 (1.00) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL17898118 | 0.81 | ALOX15 (1.00) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784230-B1 | THE USE OF TERPENIC COUMARINE DERIVATIVE MOLECULES IN THE TREATMENT OF CANCER DISEASE | T C ISTANBUL MEDIPOL UNIV (TR) | 2022-11-30 | — | — | EP | disclosed |