NDUFB9

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 · Q9Y6M9 · NDUFB9 on Sugi Atlas →

199 patent compounds predicted against NDUFB9, 74 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL15258558	0.76	8/20
R-(+)-Marmin (SCHEMBL27804600)	0.83	7/20
R-(+)-Marmin (SCHEMBL29353819)	0.83	7/20
R-(+)-Marmin (SCHEMBL29625637)	0.83	7/20
SCHEMBL12362713	0.77	7/20
SCHEMBL15080621	0.77	7/20
SCHEMBL12362702	0.73	7/20
SCHEMBL31179835	0.59	7/20
SCHEMBL31000416	0.78	6/20
SCHEMBL29999425	0.83	5/20
SCHEMBL24700226	0.81	5/20
SCHEMBL25269817	0.68	5/20
SCHEMBL14437596	0.57	5/20
SCHEMBL14437626	0.57	5/20
SCHEMBL14515244	0.57	5/20
Farnesiferol C (SCHEMBL12362724)	0.58	4/20
Farnesiferol C (SCHEMBL30290981)	0.58	4/20
Farnesiferol (SCHEMBL30497786)	0.58	4/20
Farnesiferol C (SCHEMBL31238183)	0.58	4/20
SCHEMBL28061786	0.58	3/20

Clinical trials — most relevant to NDUFB9 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
A Study of Efficacy, Safety and Tolerability of Idebenone in the Treatment of Friedreich's Ataxia (FRDA) Patients	PHASE3	COMPLETED
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease	PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
Parkinson's Disease Treatment With Coenzyme Q10	PHASE2	COMPLETED
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome	PHASE1/PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Nicotinamide Riboside in Ulcerative Colitis	nan	RECRUITING
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection	nan	COMPLETED
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Pharmacokinetic Study on Three Formulations of Coenzyme Q10 With Different Carriers	nan	UNKNOWN
A RETROspective Study of Patients With TK2d	nan	COMPLETED
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis	nan	COMPLETED
Ccf mtDNA as a Neurodegenerative Biomarker	nan	UNKNOWN
Cardiac Mitochondrial Function in Explanted Human Hearts	nan	UNKNOWN
Q10 Ubiquinol in Autism Spectrum Disorder and in Phelan-McDermid Syndrome.	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a NDUFB9 binder may also engage these)

Protein	Name	Similarity
Q0MQE9	—	1.000	Q0MQE9 →
Q0MQF0	—	1.000	Q0MQF0 →
Q0MQE8	—	1.000	Q0MQE8 →
Q02369	—	1.000	Q02369 →
Q9CQJ8	—	1.000	Q9CQJ8 →
A9UMQ3	—	0.993	A9UMQ3 →
Q54NR3	—	0.991	Q54NR3 →
B5X5L2	—	0.988	B5X5L2 →
B5FYC7	—	0.987	B5FYC7 →
Q945M1	—	0.986	Q945M1 →
Q6DGP7	—	0.986	Q6DGP7 →
B2RYU8	—	0.985	B2RYU8 →
Q9CQB7	—	0.984	Q9CQB7 →
Q6CAD1	—	0.984	Q6CAD1 →
Q9VMX0	—	0.983	Q9VMX0 →
Q86IZ2	—	0.983	Q86IZ2 →
O43325	—	0.983	O43325 →
Q9Y7R1	—	0.983	Q9Y7R1 →
NDUFB4	NADH dehydrogenase [ubiquinone] 1 beta subcom	0.982	landscape →
P49391	—	0.981	P49391 →
P48306	—	0.981	P48306 →
Q9UT54	—	0.981	Q9UT54 →
Q75AY1	—	0.981	Q75AY1 →
Q18359	—	0.981	Q18359 →
Q9BYN8	—	0.981	Q9BYN8 →
Q7RXU7	—	0.981	Q7RXU7 →
Q0MQD4	—	0.980	Q0MQD4 →
Q0MQD5	—	0.980	Q0MQD5 →
O43089	—	0.980	O43089 →
B5XCZ6	—	0.980	B5XCZ6 →