Sugi Predict
/ Targets
/ TPP2
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to TPP2 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| The Effect of Sitagliptin, Pioglitazone and Dapagliflozine on Myocardial Infarction in Diabetic Rats |
PHASE4 | COMPLETED |
| Effect of Sitagliptin and an ACE Inhibitor on Blood Pressure in Metabolic Syndrome |
PHASE4 | COMPLETED |
| The Effect of Saxagliptin on Glucose Fluctuation and Immune Regulation in Patients With Type 1 Diabetes |
PHASE4 | UNKNOWN |
| Study of the QOL Evaluation of Trelagliptin in Patients With Type 2 Diabetes Mellitus |
PHASE4 | COMPLETED |
| Sitagliptin and Endothelial Dysfunction |
PHASE3 | UNKNOWN |
| The Impact of Sitagliptin as an Add on Therapy With Closed Loop Control in Adolescents With Diabetic Nephropathy |
PHASE3 | COMPLETED |
| Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus |
PHASE2 | COMPLETED |
| A First-in-Human, Open-Label, Dose-Escalation Study to Evaluate the Safety and Tolerability of Gene Therapy With TTX-381 for the Ocular Manifestations Associated With Neuronal Ceroid Lipofuscinosis Type 2 (CLN2) Disease |
PHASE1/PHASE2 | RECRUITING |
| Effect of Evogliptin on Albuminuria in Patients With Type 2 Diabetes and Renal Insufficiency |
PHASE2 | COMPLETED |
| Efficacy of SYR-472 in Subjects With Type 2 Diabetes Mellitus |
PHASE2 | COMPLETED |
| Effects of Dapagliflozin+Saxagliptin in Addition to Metformin v/s Saxagliptin or Dapagliflozin in Patients With DM2. |
PHASE2 | COMPLETED |
| Safety Study of a Gene Transfer Vector for Children With Late Infantile Neuronal Ceroid Lipofuscinosis |
PHASE1 | COMPLETED |
| Study of HuCNS-SC Cells in Patients With Infantile or Late Infantile Neuronal Ceroid Lipofuscinosis (NCL) |
PHASE1 | COMPLETED |
| Effect of Sitagliptin on Incretin Effect in Patients With Type 2 Diabetes Mellitus |
PHASE1 | COMPLETED |
| Pappalysin 2 (PAPP-A2) Enzyme Replacement |
PHASE1 | COMPLETED |
| Randomized Trial Comparing Sitagliptin to Placebo in Closed Loop |
PHASE1 | COMPLETED |
| Genetic and Morphological Analysis of Thyrotoxic Periodic Paralysis |
nan | UNKNOWN |
| Longitudinal Assessment of Atypical Tripeptidyl Peptidase 1 Enzyme Deficiency Patients |
nan | ACTIVE_NOT_RECRUITING |
| Genetic Analysis of Thyrotoxic Periodic Paralysis |
nan | COMPLETED |
| Genetic Studies of Lysosomal Storage Disorders |
nan | ENROLLING_BY_INVITATION |
| ProGRP, CgA, NSE and TUM2-PK in in Patients With Neuroendocrine Tumors |
nan | UNKNOWN |
| A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders |
nan | RECRUITING |
| Influence of DPP-4 on Inflammatory Parameters in Diabetics: Gender Aspects |
nan | UNKNOWN |
| DPP4 Activity, Microvascular Reactivity and Inflammation |
nan | COMPLETED |
| Ovarian Reserve and Matrix Metalloproteinases |
nan | COMPLETED |
| Effect of Dipeptidyl-4 Inhibitors in Reducing Stroke Severity, From HIRA Database |
nan | UNKNOWN |
| Early Check: Expanded Screening in Newborns |
nan | ENROLLING_BY_INVITATION |
| InsightRP2 Registry |
nan | RECRUITING |
| Effect of Dipeptidyl Peptidase IV After Diets in näive Type 2 Diabetic Patients |
nan | COMPLETED |
| Exploring Biomarkers in Hereditary Transthyretin Amyloidosis |
nan | RECRUITING |
Related proteins — ESM-2 sequence neighbours (a TPP2 binder may also engage these)