Sugi Predict

Sugi Predict / Targets / PLD4

PLD4

5'-3' exonuclease PLD4 · Q96BZ4 · PLD4 on Sugi Atlas →

0 patent compounds predicted against PLD4, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PLD4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Predicting the Response to Montelukast by Genetic Variation in Asthmatics PHASE3COMPLETED
IN10018 in Combination With Pegylated Liposomal Doxorubicin (PLD) vs. Placebo in Combination With PLD for the Treatment of Platinum-resistant Recurrent Ovarian Cancer PHASE2RECRUITING
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
PET Whole Body Biodistribution and Test Retest Bain Imaging Studies Using a Phosphodiesterase 4 Inhibitor (R)-[11C]Rolipram PHASE1COMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
PET Imaging of DHA Metabolism nanCOMPLETED
Mucomyst for Hepatitis C nanSUSPENDED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Identification of a New Gene Involved in Hereditary Lipodystrophy nanCOMPLETED
The Association Between Post-ERCP Acute Pancreatitis and Various Genetic Mutations nanCOMPLETED
Genetics and Psychopathology in the 22q11 Deletion Syndrome nanUNKNOWN
Lipa Gene Mutation in PED-LIPIGEN (Pediatric FH Subjects) nanUNKNOWN
Genetic Investigation of Cancer Predisposition nanNOT_YET_RECRUITING
Investigation of Copy Number Variations and Genetic Variants in POI nanRECRUITING
Characterization of Microbiological and Genetic Features in Prostate Cancer and Their Association with Disease Stage nanENROLLING_BY_INVITATION
PCD New Gene Discovery nanCOMPLETED
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia nanUNKNOWN
Genetic Studies of Lysosomal Storage Disorders nanENROLLING_BY_INVITATION
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease. nanUNKNOWN
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes nanCOMPLETED
Study of Constitutional Platelet Disease nanUNKNOWN
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Identification of an Asthma Susceptibility Gene on 3P nanCOMPLETED
Germline Mutations in Pancreatic Adenocarcinoma nanCOMPLETED
for Adipose Tissue DIabetes VAriants (fATDIVA) nanCOMPLETED
A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients nanCOMPLETED
Family Myopia Study nanCOMPLETED
Prospective Genetic Study in Patients With Ovarian Insufficiency nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a PLD4 binder may also engage these)

ProteinNameSimilarity
Q5FVH2 — 0.993 Q5FVH2 →
Q8BG07 — 0.990 Q8BG07 →
PLD3 5'-3' exonuclease PLD3 0.988 landscape →
O35405 — 0.985 O35405 →
Q2KJJ8 — 0.982 Q2KJJ8 →
Q5R4Y7 — 0.981 Q5R4Y7 →
Q4R583 — 0.981 Q4R583 →
Q0V8J4 — 0.973 Q0V8J4 →
A1L1C2 — 0.972 A1L1C2 →
Q13724 — 0.971 Q13724 →
Q9JHA8 — 0.971 Q9JHA8 →
Q9Y334 — 0.970 Q9Y334 →
Q9JKV7 — 0.970 Q9JKV7 →
Q6MG64 — 0.970 Q6MG64 →
Q643R3 — 0.970 Q643R3 →
Q91V24 — 0.969 Q91V24 →
Q8VDP3 — 0.969 Q8VDP3 →
Q28DT3 — 0.969 Q28DT3 →
Q80XS7 — 0.969 Q80XS7 →
Q7TNJ2 — 0.968 Q7TNJ2 →
P0C0K6 — 0.968 P0C0K6 →
Q6P5W5 — 0.968 Q6P5W5 →
Q8BNJ2 — 0.968 Q8BNJ2 →
A3KNW0 — 0.968 A3KNW0 →
Q92935 — 0.968 Q92935 →
Q9R0S3 — 0.968 Q9R0S3 →
Q2KHV9 — 0.968 Q2KHV9 →
Q68DD2 — 0.967 Q68DD2 →
Q8IZY2 — 0.967 Q8IZY2 →
Q8TDZ2 — 0.967 Q8TDZ2 →