Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22010877 | 0.91 | PRDX1 (0.63) | PRDX1NR4A1 | |
| SCHEMBL18781883 | 0.90 | PRDX1 (0.83) | PRDX1NR4A1 | |
| SCHEMBL22010596 | 0.89 | PRDX1 (0.67) | PRDX1NR4A1 | |
| SCHEMBL20371742 | 0.87 | NR4A1 (0.82) | PRDX1NR4A1 | |
| SCHEMBL22011631 | 0.85 | PRDX1 (0.57) | PRDX1NR4A1 | |
| SCHEMBL21529185 | 0.84 | NR4A1 (0.78) | NR4A1 | |
| SCHEMBL22010874 | 0.83 | HSP90AA1 (0.77) | NR4A1 | |
| SCHEMBL23490905 | 0.83 | NR4A1 (0.70) | PRDX1NR4A1 | |
| SCHEMBL22010584 | 0.83 | TERT (0.79) | NR4A1 | |
| SCHEMBL22011634 | 0.83 | NR4A1 (0.79) | PRDX1NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753436-B2 | Analogs of celastrol | ERX PHARMACEUTICALS CORPORATION (US) | 2023-09-12 | — | — | US | disclosed |
| US-10662218-B2 | Analogs of celastrol | ERX PHARMACEUTICALS CORPORATION | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662218-B2 | Analogs of celastrol | GIPR, GPR119, EBP | PRDX1 4176/4885NR4A1 1945/4885 |
| US-11753436-B2 | Analogs of celastrol | GIPR, GPR119, EBP | PRDX1 4176/4885NR4A1 1945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.