RARS2

Probable arginine--tRNA ligase, mitochondrial · Q5T160 · RARS2 on Sugi Atlas →

0 patent compounds predicted against RARS2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to RARS2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Pilot Study of an Antioxidant Cocktail vs. Placebo in the Treatment of Children and Adolescents With Rett Syndrome PHASE2NOT_YET_RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome PHASE1/PHASE2COMPLETED
Efficacy and Safety of Drug Combination Therapy of Isotretinoin and Some Antifungal Drugs as A Potential Aerosol Therapy for COVID-19 : An Innovative Therapeutic Approach COVID-19 PHASE2UNKNOWN
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)? PHASE1UNKNOWN
Natural History Study of Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation (LBSL) nanRECRUITING
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Mitochondrial Disease-associated ImmunoDeficiencies nanRECRUITING
Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells nanRECRUITING
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes nanNOT_YET_RECRUITING
Collection of Samples of Bone Marrow Aspiration From Patients With Myelodysplastic Syndrome nanACTIVE_NOT_RECRUITING
Mitochondrial Dysfunction in Phelan-McDermid Syndrome nanCOMPLETED
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases nanCOMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases nanRECRUITING
Natural History in Primary Mitochondrial Myopathies nanRECRUITING
The Genetics of Diabetes in Southern California Chinese Americans nanWITHDRAWN
Exploring the Relationship Between Androgen Metabolism, Metabolic Disease and Skeletal Muscle Energy Balance in Men nanUNKNOWN
Effect of Short-Term Exercise Training on ATP Synthesis in Relatives of Type 2 Diabetic Humans nanCOMPLETED
Mitochondria and Metabolic Syndrome in a Southern California Chinese Cohort nanCOMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip nanCOMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) nanRECRUITING
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS nanRECRUITING
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction nanCOMPLETED
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders nanCOMPLETED
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy nanCOMPLETED
Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis nanUNKNOWN
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a RARS2 binder may also engage these)

ProteinNameSimilarity
Q5REH3 1.000 Q5REH3 →
Q0P5H7 1.000 Q0P5H7 →
Q3U186 0.999 Q3U186 →
Q6GQJ7 0.993 Q6GQJ7 →
Q8VDC0 0.982 Q8VDC0 →
P38714 0.978 P38714 →
Q15031 0.977 Q15031 →
IARS2 Isoleucine--tRNA ligase, mitochondrial 0.976 landscape →
Q6PF21 0.976 Q6PF21 →
Q2T9L8 0.975 Q2T9L8 →
Q5RDP4 0.973 Q5RDP4 →
A6H7E1 0.972 A6H7E1 →
Q6MG21 0.971 Q6MG21 →
Q8BIJ6 0.971 Q8BIJ6 →
Q5R8R3 0.971 Q5R8R3 →
Q8R123 0.970 Q8R123 →
B3DLB3 0.970 B3DLB3 →
Q8BYM8 0.970 Q8BYM8 →
Q6P6V7 0.970 Q6P6V7 →
D9IVE5 0.970 D9IVE5 →
Q68FL6 0.970 Q68FL6 →
Q90YI3 0.969 Q90YI3 →
P13705 0.969 P13705 →
P49696 0.969 P49696 →
E1BMP7 0.969 E1BMP7 →
Q0P4R5 0.969 Q0P4R5 →
Q66KB7 0.969 Q66KB7 →
F4IPY2 0.968 F4IPY2 →
Q5R6R6 0.968 Q5R6R6 →
Q9HA77 0.968 Q9HA77 →