RNF5

E3 ubiquitin-protein ligase RNF5 · Q99942 · RNF5 on Sugi Atlas →

0 patent compounds predicted against RNF5, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to RNF5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study PHASE3COMPLETED
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma PHASE2WITHDRAWN
Phase II Prospective Cohort Study of Intravesical Recombinant Human Type 5 Adenovirus Injection for Treatment of High-Risk Non-Muscle Invasive Bladder Cancer: Evaluating Efficacy and Safety PHASE2NOT_YET_RECRUITING
Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma PHASE2SUSPENDED
Phase II Study of Vandetanib in Individuals With Kidney Cancer PHASE2COMPLETED
LCL161 in Treating Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocytosis Myelofibrosis PHASE2COMPLETED
Oral Nitrite for Older Heart Failure Patients PHASE2COMPLETED
A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001) PHASE2COMPLETED
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes PHASE2UNKNOWN
Olaparib in Patients With HRD Malignant Mesothelioma PHASE2RECRUITING
Relapsed and/or Refractory Non-Hodgkin Lymphoma Study PHASE2WITHDRAWN
A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7248824 in Participants With Angelman Syndrome (AS) PHASE1COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma EARLY_PHASE1RECRUITING
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin nanUNKNOWN
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors nanNOT_YET_RECRUITING
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Clinical Trial of Levodopa/Carbidopa ( Sinemet) Therapy in Angel Man Syndrome nanCOMPLETED
Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1 nanRECRUITING
Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome nanRECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome nanRECRUITING
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma nanCOMPLETED
Genetic Variation in TRAF3IP2 (rs13190932) nanRECRUITING
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure nanCOMPLETED
Prognostic Value of Combined Approach Based on KEAP1/NFE2L2 Mutations and Pre-therapeutic FDG-PET/CT Radiomic Analysis in Advanced Non-small-cell Lung Cancer PDL1 ≥ 50% Treated With Pembrolizumab (PEMBROMIC) nanUNKNOWN
Establishment of a Prospective Clinical-biological Database nanRECRUITING
Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit nanCOMPLETED
The Crosstalk Between the Epigenome and Mitochondria in SCI nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a RNF5 binder may also engage these)

ProteinNameSimilarity
Q5M807 1.000 Q5M807 →
O35445 1.000 O35445 →
Q5RFK9 0.991 Q5RFK9 →
Q96GF1 0.991 Q96GF1 →
Q568Y3 0.988 Q568Y3 →
Q6PC78 0.988 Q6PC78 →
Q91YT2 0.986 Q91YT2 →
Q5ZIR9 0.982 Q5ZIR9 →
Q5XIL0 0.979 Q5XIL0 →
Q09463 0.978 Q09463 →
P98154 0.978 P98154 →
Q3U2C5 0.977 Q3U2C5 →
O43900 0.976 O43900 →
Q8NC42 0.976 Q8NC42 →
Q8QZV2 0.975 Q8QZV2 →
Q7TQH7 0.975 Q7TQH7 →
P98153 0.975 P98153 →
Q6ZPS6 0.974 Q6ZPS6 →
Q1L8G6 0.973 Q1L8G6 →
Q9H6Y7 0.973 Q9H6Y7 →
Q5RBA5 0.973 Q5RBA5 →
Q8BY98 0.973 Q8BY98 →
Q5T124 0.973 Q5T124 →
O08623 0.973 O08623 →
Q6UWI4 0.973 Q6UWI4 →
Q3TQF0 0.972 Q3TQF0 →
O75064 0.972 O75064 →
Q66HA1 0.972 Q66HA1 →
SQSTM1 Sequestosome-1 0.972 landscape →
Q80XI6 0.972 Q80XI6 →