SCHEMBL9595149

SCHEMBL9595149

NC(=O)c1sc2ccccc2c1OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SENP2 Q9HC62 18/20 0.56
SENP1 Q9P0U3 18/20 0.56
SENP5 Q96HI0 17/20 0.56
USP2 O75604 1/20 0.56
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
IKBKB O14920 1/20 0.53
LIMK1 P53667 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4634951 0.88 KDM4E (0.67) SENP2SENP1SENP5USP2KDM4E
SCHEMBL4604537 0.84 SENP2 (0.60) SENP2SENP1SENP5USP2KDM4E
SCHEMBL8442498 0.83 ICAM1 (0.61) SENP2SENP1SENP5USP2
SCHEMBL5034495 0.83 SENP5 (0.59) SENP2SENP1SENP5USP2KDM4E
SCHEMBL4633875 0.81 ALDH1A1 (0.67) SENP2SENP1SENP5USP2KDM4E
SCHEMBL9214257 0.80 LIMK1 (0.53) SENP2SENP1SENP5KDM4EALDH1A1
SCHEMBL4632950 0.80 SENP5 (0.60) SENP2SENP1SENP5USP2KDM4E
SCHEMBL4634430 0.80 SENP2 (0.59) SENP2SENP1SENP5USP2KDM4E
SCHEMBL4632927 0.80 SENP2 (0.59) SENP2SENP1SENP5USP2KDM4E
SCHEMBL9024369 0.79 LIMK1 (0.51) SENP2SENP1SENP5KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5208253-A Antiinflammatory agents WARNER-LAMBERT COMPANY (US) 1993-05-04 US disclosed