SERPINB6

Serpin B6 · P35237 · SERPINB6 on Sugi Atlas →

0 patent compounds predicted against SERPINB6, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SERPINB6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Metformin Use in Cardiac Fibrosis in PAI-1 Deficiency PHASE4ACTIVE_NOT_RECRUITING
A Study to Evaluate the Safety and Effect of Escalating Doses of CINRYZE PHASE4COMPLETED
Berinert P Study of Subcutaneous Versus Intravenous Administration PHASE3COMPLETED
Donidalorsen Treatment in Children With Hereditary Angioedema PHASE3RECRUITING
The Safety and Tolerability of Alpha-1 Modified Process (MP) In Subjects With Alpha-1-antitrypsin (AAT) Deficiency PHASE3COMPLETED
International Study Evaluating the Safety and Efficacy of Inhaled, Human, Alpha-1 Antitrypsin (AAT) in Alpha-1 Antitrypsin Deficient Patients With Emphysema PHASE2/PHASE3COMPLETED
Bradykinin Receptor Antagonism During Cardiopulmonary Bypass PHASE2/PHASE3COMPLETED
A Study of Icatibant (TAK-667) in Japanese Children and Teenagers With Acute Attacks of Hereditary Angioedema PHASE3COMPLETED
A Gene Therapy Study of BMN 331 in Subjects With Hereditary Angioedema PHASE1/PHASE2ACTIVE_NOT_RECRUITING
The Safety and Tolerability of SerpinPC in Healthy Men and in Men with Severe Blood Disorders (haemophilia a and B) PHASE1/PHASE2COMPLETED
Short-course Radiotherapy Combined With Serplulimab and Chemotherapy as Neoadjuvant Treatment for Resectable ESCC PHASE2NOT_YET_RECRUITING
Feasibility of Retinoic Acid Treatment in Emphysema (FORTE) PHASE2COMPLETED
JDB153 Combined With Serplulimab for Pancreatic Cancer After Standard Treatment Failure PHASE1/PHASE2NOT_YET_RECRUITING
A Study to Evaluate Serplulimab in Combination With Docetaxel +S-1 VS. Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage IIIc Gastric Cancer PHASE2UNKNOWN
A Phase II Study to Evaluate the Efficacy and Safety of HLX43 + Serplulimab as Neoadjuvant Therapy in Subjects With NSCLC PHASE2RECRUITING
Long Term Treatment Effect of the Safety, Tolerability and Efficacy of AAT in Type 1 Diabetes PHASE2COMPLETED
Intravenous Alpha-1 Antitrypsin for Hospitalized Patients With COPD Exacerbations (AECOPD Study) PHASE2NOT_YET_RECRUITING
Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery PHASE1/PHASE2UNKNOWN
Identification and Characterization of Genetic Variants in Hereditary Angioedema nanNOT_YET_RECRUITING
Belgian Antithrombin Deficiency Registry nanNOT_YET_RECRUITING
Involvement of Monocytic B1 and B2 Receptors in Inflammation and Chronic Vascular Disease in Patients With Hereditary Bradykinetic Angioedema nanCOMPLETED
SerpinB3 Expression, PAR2 and SCCA-PD Polymorphism in Acute Respiratory Distress Syndrome nanRECRUITING
Alpha-1 Carrier Genomics Study nanCOMPLETED
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD) nanCOMPLETED
Angioedema Biomarker Research Study nanUNKNOWN
Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals nanCOMPLETED
Detecting Abnormal Blood Clotting in Patients With Metastatic Cancer Undergoing Surgery nanCOMPLETED
The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) Study nanRECRUITING
Biomarker for Hereditary AngioEdema Disease nanCOMPLETED
Alpha1-antitrypsin Deficiency Registry nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SERPINB6 binder may also engage these)

ProteinNameSimilarity
Q4R3G2 1.000 Q4R3G2 →
Q5R899 1.000 Q5R899 →
Q60854 0.996 Q60854 →
O02739 0.987 O02739 →
P05619 0.979 P05619 →
SERPINB8 Serpin B8 0.973 landscape →
SERPINB1 Leukocyte elastase inhibitor 0.962 landscape →
Q4G075 0.959 Q4G075 →
Q8VHP7 0.955 Q8VHP7 →
Q1JPB0 0.949 Q1JPB0 →
Q9D154 0.949 Q9D154 →
P80229 0.947 P80229 →
P50453 0.941 P50453 →
Q5BIR5 0.940 Q5BIR5 →
O08800 0.936 O08800 →
Q5I0S8 0.905 Q5I0S8 →
Q5SV42 0.898 Q5SV42 →
P17475 0.896 P17475 →
O54763 0.895 O54763 →
O00394 0.893 O00394 →
P50447 0.891 P50447 →
O54760 0.890 O54760 →
P97277 0.890 P97277 →
P12725 0.886 P12725 →
P01009 0.884 P01009 →
P01010 0.884 P01010 →
P34955 0.883 P34955 →
Q5RCW5 0.882 Q5RCW5 →
O54761 0.879 O54761 →
O54758 0.879 O54758 →