SERPINB8

Serpin B8 · P50452 · SERPINB8 on Sugi Atlas →

0 patent compounds predicted against SERPINB8, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SERPINB8 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Assessment of Coagulation Abnormalities in Acute on Chronic Liver Failure Patients Using Thromboelastography PHASE4UNKNOWN
Metformin Use in Cardiac Fibrosis in PAI-1 Deficiency PHASE4ACTIVE_NOT_RECRUITING
Serplulimab Combined With Nab-paclitaxel and Cisplatin in Neoadjuvant Therapy for Resectable Esophageal Squamous Cell Carcinoma PHASE4NOT_YET_RECRUITING
Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema PHASE2/PHASE3WITHDRAWN
Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery PHASE1/PHASE2UNKNOWN
The Safety and Tolerability of SerpinPC in Healthy Men and in Men with Severe Blood Disorders (haemophilia a and B) PHASE1/PHASE2COMPLETED
A Study to Evaluate Serplulimab in Combination With Docetaxel +S-1 VS. Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage IIIc Gastric Cancer PHASE2UNKNOWN
Serplulimab Combined With Concurrent Chemoradiotherapy for Locally Advanced Treatment Esophageal Cancer in Old Age PHASE2RECRUITING
A Phase II Study to Evaluate the Efficacy and Safety of HLX43 + Serplulimab as Neoadjuvant Therapy in Subjects With NSCLC PHASE2RECRUITING
Intravenous Alpha-1 Antitrypsin for Hospitalized Patients With COPD Exacerbations (AECOPD Study) PHASE2NOT_YET_RECRUITING
Alvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin Deficiency PHASE2COMPLETED
Digoxin for Congenital Erythrocytosis Due to Up-Regulated Hypoxia Sensing PHASE1WITHDRAWN
Peri-implantitis and MMP-8 nanCOMPLETED
Belgian Antithrombin Deficiency Registry nanNOT_YET_RECRUITING
SerpinB3 Expression, PAR2 and SCCA-PD Polymorphism in Acute Respiratory Distress Syndrome nanRECRUITING
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD) nanCOMPLETED
Alpha-1 Carrier Genomics Study nanCOMPLETED
Study of Individuals Affected With Hypoplasminogenemia nanRECRUITING
Identification and Characterization of Genetic Variants in Hereditary Angioedema nanNOT_YET_RECRUITING
Genetic Determinism of Epithelial Barrier Defects in Irritable Bowel Syndrome nanWITHDRAWN
Natural Course and Molecular Basis of Alpha 1- Antitrypsin Deficiency-associated Liver Disease. nanNOT_YET_RECRUITING
Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals nanCOMPLETED
Genomic Research in Alpha-1 Antitrypsin Deficiency nanCOMPLETED
Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis nanRECRUITING
Screening for Alpha-1 Antitrypsin Deficiency in Patients With Airway Obstruction nanRECRUITING
Disorders of the Acute Phase Response Following Trauma and Invasive Surgery nanENROLLING_BY_INVITATION
The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) Study nanRECRUITING
Monitoring of Chronic Conditions in Breast Cancer nanRECRUITING
Biomarkers of Lichen Sclerosus nanUNKNOWN
Apoptotic Changes in Gingiva Caused by Smoking nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SERPINB8 binder may also engage these)

ProteinNameSimilarity
Q8VHP7 0.988 Q8VHP7 →
Q4G075 0.986 Q4G075 →
Q5BIR5 0.986 Q5BIR5 →
O08800 0.984 O08800 →
SERPINB1 Leukocyte elastase inhibitor 0.983 landscape →
P50453 0.982 P50453 →
Q60854 0.982 Q60854 →
Q1JPB0 0.980 Q1JPB0 →
Q9D154 0.980 Q9D154 →
O02739 0.979 O02739 →
SERPINB6 Serpin B6 0.974 landscape →
P05619 0.972 P05619 →
P80229 0.971 P80229 →
Q5R899 0.966 Q5R899 →
Q4R3G2 0.966 Q4R3G2 →
Q5SV42 0.961 Q5SV42 →
Q5I0S8 0.957 Q5I0S8 →
P48594 0.943 P48594 →
Q9UIV8 0.940 Q9UIV8 →
Q52L45 0.940 Q52L45 →
P29508 0.939 P29508 →
B4USX2 0.936 B4USX2 →
O00394 0.935 O00394 →
P17475 0.934 P17475 →
P97277 0.932 P97277 →
P01013 0.931 P01013 →
P01009 0.929 P01009 →
P34955 0.928 P34955 →
P12725 0.928 P12725 →
O54763 0.928 O54763 →