Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.83 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.83 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.54 |
| ▸ | IDH2 | P48735 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 3/20 | 0.52 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.52 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.52 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128814 | 0.91 | SLC20A2 (1.00) | SLC20A2SLC20A1RXFP1IDH2AVPR2 | |
| SCHEMBL5115424 | 0.89 | SLC20A2 (0.66) | SLC20A2SLC20A1RXFP1IDH2CNR2 | |
| SCHEMBL5117189 | 0.86 | SLC10A6 (0.72) | SLC20A2SLC20A1RXFP1CNR2AVPR2 | |
| SCHEMBL5119995 | 0.85 | RXFP1 (0.70) | SLC20A2SLC20A1RXFP1AVPR2GPR27 | |
| SCHEMBL5120085 | 0.85 | SLC20A2 (0.63) | SLC20A2SLC20A1AVPR2GPR27SLC10A2 | |
| SCHEMBL7631719 | 0.83 | SLC20A2 (0.86) | SLC20A2SLC20A1RXFP1AVPR2GPR27 | |
| SCHEMBL10249599 | 0.80 | GPR27 (0.66) | SLC20A2SLC20A1AVPR2GPR27SLC10A2 | |
| SCHEMBL5110940 | 0.80 | SLC10A6 (0.68) | SLC20A2SLC20A1AVPR2GPR27SLC10A2 | |
| SCHEMBL5125728 | 0.80 | SLC10A6 (0.61) | SLC20A2SLC20A1AVPR2GPR27SLC10A2 | |
| SCHEMBL6862230 | 0.80 | SLC20A2 (0.66) | SLC20A2SLC20A1AVPR2GPR27SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216449-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-20 | — | — | US | claimed |
| EP-1202729-A1 | PHOSPHATE TRANSPORT INHIBITORS | SmithKline Beecham Corporation (US) | 2002-05-08 | — | — | EP | claimed |
| WO-2001087294-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |
| WO-2001005398-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-25 | — | — | WO | claimed |
| US-20030216449-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-20 | — | — | US | disclosed |
| EP-1202729-A1 | PHOSPHATE TRANSPORT INHIBITORS | SmithKline Beecham Corporation (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001087294-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-22 | — | — | WO | disclosed |
| WO-2001005398-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216449-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC34A3 | SLC20A2 4/4885SLC20A1 5/4885RXFP1 2419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.