Sugi Predict

Sugi Predict / Targets / SPEN

SPEN

Msx2-interacting protein · Q96T58 · SPEN on Sugi Atlas →

0 patent compounds predicted against SPEN, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SPEN by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment PHASE2/PHASE3RECRUITING
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure PHASE2COMPLETED
GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS) PHASE2COMPLETED
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Phase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDS PHASE1UNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
The Role of TBX3 in Human ES Cell Differentiation nanWITHDRAWN
Genetic Causes and Clinical Features of Childhood Interstitial Lung Diseases in China nanCOMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Immunophenotyping and Xist Gene in AML nanUNKNOWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
Study of Genetic Risk Factors for Spina Bifida and Anencephaly nanUNKNOWN
Genetics and Psychopathology in the 22q11 Deletion Syndrome nanUNKNOWN
Effect of Mechanical Ventilation on Plasma Concentration Level of R-spondin Proteins nanCOMPLETED
is the Sclerostin Marker of Chronic Periodontitis nanCOMPLETED
Biocollection in MyeloDysplastic Syndrome (P-MDS) nanRECRUITING
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study nanUNKNOWN
Collection of Blood Samples for DNA in Motor Neuron Disease nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Hirschsprung Disease Genetic Study nanRECRUITING
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN) nanRECRUITING
Hereditary Tubulointerstitial Nephritis nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
The Genetics of Chiari Type I Malformation nanCOMPLETED
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a SPEN binder may also engage these)

ProteinNameSimilarity
Q62504 — 1.000 Q62504 →
Q9CSP9 — 0.992 Q9CSP9 →
Q14AX6 — 0.992 Q14AX6 →
Q3MJK5 — 0.991 Q3MJK5 →
P30415 — 0.990 P30415 →
P97868 — 0.990 P97868 →
YTHDC1 YTH domain-containing protein 1 0.989 landscape →
PPHLN1 Periphilin-1 0.989 landscape →
TTC14 Tetratricopeptide repeat protein 14 0.988 landscape →
Q10B98 — 0.988 Q10B98 →
Q66J90 — 0.988 Q66J90 →
Q5HZJ0 — 0.987 Q5HZJ0 →
Q6E3D4 — 0.987 Q6E3D4 →
Q9NRR4 — 0.987 Q9NRR4 →
E9Q5K9 — 0.987 E9Q5K9 →
E1BB50 — 0.987 E1BB50 →
P78332 — 0.986 P78332 →
B5DE93 — 0.986 B5DE93 →
Q9D824 — 0.986 Q9D824 →
A0A0R4IZ84 — 0.986 A0A0R4IZ84 →
Q3KPW4 — 0.986 Q3KPW4 →
B0BN49 — 0.986 B0BN49 →
P30414 — 0.986 P30414 →
O14161 — 0.986 O14161 →
Q80TZ9 — 0.985 Q80TZ9 →
Q6PCT5 — 0.985 Q6PCT5 →
Q7YZA2 — 0.985 Q7YZA2 →
Q99NE5 — 0.985 Q99NE5 →
Q8VY74 — 0.985 Q8VY74 →
O13845 — 0.985 O13845 →